Nanomedicine-fortified cosmeceutical serums for the mitigation of psoriasis and acne

Papers of special note have been highlighted as: • of interest; •• of considerable interest

References

• 1. Salvioni L, Morelli L, Ochoa E et al. The emerging role of nanotechnology in skin care. Adv. Colloid Interface Sci. 293, doi:10.1016/j.cis.2021.102437 (2021) (Epub ahead of print).
  MedlineGoogle Scholar
• 2. Zaleski-Larsen LA, Fabi SG, McGraw T, Taylor M. Acne scar treatment: a multimodality approach tailored to scar type. Dermatol. Surg. 42(Suppl. 2), S139–S149 (2016).
  Medline CASGoogle Scholar
• 3. Sherrow V. For Appearance's Sake: The Historical Encyclopedia of Good Looks, Beauty, and Grooming. Greenwood Publishing Group, AZ, USA (2001).
  Google Scholar
• 4. Dhawan A, Sharma V, Parmar D. Nanomaterials: a challenge for toxicologists. Nanotoxicology 3(1), 1–9 (2009).
  CASGoogle Scholar
• 5. Mayoral FA, Kenner JR, Draelos ZD. The skin health and beauty pyramid: a clinically based guide to selecting topical skincare products. JDD 13(4), 414–421 (2014).
  Google Scholar
• 6. Draelos ZD. The science behind skin care: moisturizers. J. Cosmet. Dermatol. 17(2), 138–144 (2018).
  MedlineGoogle Scholar
• 7. Jackson EM. Moisturizers: what's in them? How do they work? Am. J. Contact Dermat. 3(4), 162–168 (1992).
  Google Scholar
• 8. Oberdörster G, Oberdörster E, Oberdörster J. Nanotoxicology: an emerging discipline evolving from studies of ultrafine particles. Environ. Health Perspect. 113(7), 823–839 (2005).
  Medline CASGoogle Scholar
• 9. Ashaolu TJ. Nanoemulsions for health, food, and cosmetics: a review. Environ. Chem Lett. 19(4), 3381–3395 (2021).
  Medline CASGoogle Scholar
• 10. Santos AC, Morais F, Simões A et al. Nanotechnology for the development of new cosmetic formulations. Expert Opin. Drug Deliv. 16(4), 313–330 (2019).
  Medline CASGoogle Scholar
• 11. Wunnoo S, Bilhman S, Amnuaikit T et al. Rhodomyrtone as a new natural antibiotic isolated from Rhodomyrtus tomentosa leaf extract: a clinical application in the management of acne vulgaris. Antibiotics 10(2), 108 (2021). • Rhodomyrtone is potential bioactive compound have been fortified in vesicle drug-delivery system and evaluated as nanomedicine efficacy in the management of acne vulgars.
  CASGoogle Scholar
• 12. Akbari J, Saeedi M, Morteza-Semnani K et al. An eco-friendly and hopeful promise platform for delivering hydrophilic wound healing agents in topical administration for wound disorder: diltiazem-loaded niosomes. J. Pharm. Innov. 1–17 (2023) (Epub ahead of print).
  Google Scholar
• 13. Patel R, Singh S, Singh S, Sheth N, Gendle R. Development and characterization of curcumin loaded transfersome for transdermal delivery. J. Pharm. Sci. Res. 1(4), 71 (2009). •• Coucumin is a potential bioactive compound derived from curcuma longa demonstrates excellent efficacy due to multifarious biological application have been fortified within lipid-based vesicle and assessed for diffusion through skin for efficacy. Therefore the formulation is of outmost importance that indicates potency as cosmeceutical serum in management of psoriasis and acne.
  Google Scholar
• 14. Chittasupho C, Chaobankrang K, Sarawungkad A et al. Antioxidant, anti-inflammatory and attenuating intracellular reactive oxygen species activities of nicotiana tabacum var. Virginia leaf extract phytosomes and shape memory gel formulation. Gels 9(2), 78 (2023). •• Bioactive compound incorporated within lipid vesicles demonstrates enhance topical diffusion thus compound with anti-inflammatory efficacy are useful in management of acne.
  Medline CASGoogle Scholar
• 15. Chittasupho C, Ditsri S, Singh S et al. Ultraviolet radiation protective and anti-inflammatory effects of Kaempferia galanga L. rhizome oil and microemulsion: formulation, characterization, and hydrogel preparation. Gels 8(10), 639 (2022).
  Medline CASGoogle Scholar
• 16. Liu X, Xu J, Zhang H et al. Microwave-assisted synthesis of octahedral Rh nanocrystals and their performance for electrocatalytic oxidation of formic acid. RSC Adv. 13(3), 1751–1756 (2023).
  MedlineGoogle Scholar
• 17. Kaity S, Maiti S, Ghosh AK, Pal D, Ghosh A, Banerjee S. Microsponges: a novel strategy for drug delivery system. J. Adv. Pharm. Technol. Res. 1(3), 283 (2010).
  Medline CASGoogle Scholar
• 18. Alotaibi G, Alharthi S, Basu B et al. Nano-gels: recent advancement in fabrication methods for mitigation of skin cancer. Gels 9(4), 331 (2023).
  Medline CASGoogle Scholar
• 19. Bi D, Qu F, Xiao W et al. Reactive oxygen species-responsive gel-based microneedle patches for prolonged and intelligent psoriasis management. ACS Nano 17(5), 4346–4357 (2023).
  Medline CASGoogle Scholar
• 20. Jeong WY, Kwon M, Choi HE, Kim KS. Recent advances in transdermal drug delivery systems: a review. Biomater. Res. 25, 1–15 (2021).
  MedlineGoogle Scholar
• 21. Budiasih S, Masyitah I, Jiyauddin K et al. Formulation and characterization of cosmetic serum containing argan oil as moisturizing agent. Presented at: Proceedings of BROMO Conference (BROMO 2018). SCITEPRESS – Science and Technology Publications, Setúbal, Portugal, 297–304 (2018).
  Google Scholar
• 22. Todo H. Transdermal permeation of drugs in various animal species. Pharmaceutics 9, 33 (2017).
  MedlineGoogle Scholar
• 23. Lim K-M. Skin epidermis and barrier function. Int. J. Mol. Sci. 22, 3035 (2021).
  MedlineGoogle Scholar
• 24. Rochette L, Mazini L, Meloux A et al. Anti-aging effects of GDF11 on skin. Int. J. Mol. Sci. 21(7), 2958 (2020).
  MedlineGoogle Scholar
• 25. Stamu-O'Brien C, Jafferany M, Carniciu S, Abdelmaksoud A. Psychodermatology of acne: psychological aspects and effects of acne vulgaris. J. Cosmet. Dermatol. 20(4), 1080–1083 (2021).
  MedlineGoogle Scholar
• 26. Baran R. The burden of nail psoriasis: an introduction. Dermatology 221(Suppl. 1), S1–S5 (2010).
  MedlineGoogle Scholar
• 27. Williams HC, Dellavalle RP, Garner S. Acne vulgaris. Lancet 379(9813), 361–372 (2012).
  MedlineGoogle Scholar
• 28. Goulden V, Clark S, Cunliffe W. Post-adolescent acne: a review of clinical features. Br. J. Dermatol. 136(1), 66–70 (1997).
  Medline CASGoogle Scholar
• 29. Khakimova L, Abdukhamidova D, Akhmedova M, Ablakulova M. Acne in allergic skin diseases. Texas J. Med. Sci. 8, 129–131 (2022).
  Google Scholar
• 30. Pochi P. The pathogenesis and treatment of acne. Annu. Rev. Med. 41(1), 187–198 (1990).
  Medline CASGoogle Scholar
• 31. Eichenfield L, Leyden J. Acne: current concepts of pathogenesis and approach to rational treatment. Pediatrician 18(3), 218–223 (1991).
  Medline CASGoogle Scholar
• 32. Lever L, Marks R. Current views on the aetiology, pathogenesis and treatment of acne vulgaris. Drugs 39(5), 681–692 (1990).
  Medline CASGoogle Scholar
• 33. Leung AK, Barankin B, Lam JM, Leong KF, Hon KL. Dermatology: how to manage acne vulgaris. Drugs Context 10, 1–18(2021).
  Google Scholar
• 34. Tahir CM. Pathogenesis of acne vulgaris: simplified. J. Pakistan Assoc. Dermatol. 20(2), 93–97 (2010).
  Google Scholar
• 35. Leeming J, Holland K, Cunliffe W. The pathological and ecological significance of microorganisms colonising acne vulgaris comedones. J. Med. Microbiol. 20(1), 11–16 (1985).
  Medline CASGoogle Scholar
• 36. Joo SS, Jang SK, Kim SG, Choi JS, Hwang KW, Lee DI. Anti-acne activity of Selaginella involvens extract and its non-antibiotic antimicrobial potential on propionibacterium acnes. Phytother. Res. 22(3), 335–339 (2008).
  MedlineGoogle Scholar
• 37. Kim JE, Han H, Xu Y, Lee MH, Lee HJ. Efficacy of FRO on acne vulgaris pathogenesis. Pharmaceutics 15(7), 1885 (2023).
  Medline CASGoogle Scholar
• 38. Downing DT, Stewart ME, Wertz PW, Strauss JS. Essential fatty acids and acne. J. Am. Acad. Dermatol. 14(2), 221–225 (1986).
  Medline CASGoogle Scholar
• 39. Puhrel S, Sakamoto M. The chemoattractant properties of comedonal contents. J. Invest. Dermatol. 70, 353–354 (1978).
  Google Scholar
• 40. Cavallo I, Sivori F, Truglio M et al. Skin dysbiosis and Cutibacterium acnes biofilm in inflammatory acne lesions of adolescents. Sci. Rep. 12(1), (2022) (Epub ahead of print).
  Google Scholar
• 41. Heng AHS, Chew FT. Systematic review of the epidemiology of acne vulgaris. Sci. Rep. 10, 5754 (2020).
  Medline CASGoogle Scholar
• 42. Zhou X, Chen Y, Cui L, Shi Y, Guo C. Advances in the pathogenesis of psoriasis: from keratinocyte perspective. Cell Death Dis. 13(1), 81 (2022).
  Medline CASGoogle Scholar
• 43. Gottlieb SL, Gilleaudeau P, Johnson R et al. Response of psoriasis to a lymphocyte-selective toxin (DAB389IL-2) suggests a primary immune, but not keratinocyte, pathogenic basis. Nat. Med. 1(5), 442–447 (1995).
  Medline CASGoogle Scholar
• 44. Young KZ, Sarkar MK, Gudjonsson JE. Pathophysiology of generalized pustular psoriasis. Exp. Dermatol. 32(8), 1194–1203 (2023).
  Medline CASGoogle Scholar
• 45. Das RP, Jain AK, Ramesh V. Current concepts in the pathogenesis of psoriasis. Indian J. Dermatol. 54(1), 7 (2009).
  MedlineGoogle Scholar
• 46. Mehlis SL, Gordon KB. The immunology of psoriasis and biologic immunotherapy. J. Am. Acad. Dermatol. 49(2), 44–50 (2003).
  Google Scholar
• 47. Conrad C, Boyman O, Tonel G et al. α1β1 integrin is crucial for accumulation of epidermal T cells and the development of psoriasis. Nat. Med. 13(7), 836–842 (2007).
  Medline CASGoogle Scholar
• 48. Schön MP, Wilsmann-Theis D. Current developments and perspectives in psoriasis. JDDG 21(4), 363–372 (2023).
  Google Scholar
• 49. Mehta VM, Balachandran C. Biologicals in psoriasis. J. Pakistan Associ. Dermatol. 18(2), 100–109 (2008).
  Google Scholar
• 50. McGregor J, Barker J, Ross E, Macdonald D. Epidermal dendritic cells in psoriasis possess a phenotype associated with antigen presentation: in situ expression of β2-integrins. J. Am. Acad. Dermatol. 27(3), 383–388 (1992).
  Medline CASGoogle Scholar
• 51. Yamanaka K, Yamamoto O, Honda T. Pathophysiology of psoriasis: a review. J. Dermatol. 48(6), 722–731 (2021).
  Medline CASGoogle Scholar
• 52. Shortman K, Liu Y-J. Mouse and human dendritic cell subtypes. Nat. Rev. Immunol. 2(3), 151–161 (2002).
  Medline CASGoogle Scholar
• 53. Rajguru JP, Maya D, Kumar D, Suri P, Bhardwaj S, Patel ND. Update on psoriasis: a review. J. Family Med. Prim. Care 9(1), 20 (2020).
  MedlineGoogle Scholar
• 54. Longo R, Sarmiento R, Fanelli M, Capaccetti B, Gattuso D, Gasparini G. Anti-angiogenic therapy: rationale, challenges and clinical studies. Angiogenesis 5(4), 237–256 (2002).
  Medline CASGoogle Scholar
• 55. Bhushan M, McLaughlin B, Weiss J, Griffiths C. Levels of endothelial cell stimulating angiogenesis factor and vascular endothelial growth factor are elevated in psoriasis. Br. J. Dermatol. 141(6), 1054–1060 (1999).
  Medline CASGoogle Scholar
• 56. Creamer D, Sullivan D, Bicknell R, Barker J. Angiogenesis in psoriasis. Angiogenesis 5(1), 231–236 (2002).
  Medline CASGoogle Scholar
• 57. Baldwin H, Tan J. Effects of diet on acne and its response to treatment. Am. J. Clin. Dermatol. 22, 55–65 (2021).
  MedlineGoogle Scholar
• 58. Gupta V, Mohapatra S, Mishra H et al. Nanotechnology in cosmetics and cosmeceuticals – a review of latest advancements. Gels 8(3), 173 (2022).
  Medline CASGoogle Scholar
• 59. Ahmad J. Lipid nanoparticles based cosmetics with potential application in alleviating skin disorders. Cosmetics 8(3), 84 (2021).
  CASGoogle Scholar
• 60. Date A, Naik B, Nagarsenker M. Novel drug delivery systems: potential in improving topical delivery of antiacne agents. Skin Pharmacol. Physiol. 19(1), 2–16 (2005).
  Google Scholar
• 61. Münster U, Nakamuranachname C, Haberland A et al. RU 58841-myristate–prodrug development for topical treatment of acne and androgenetic alopecia. Pharmazie 60(1), 8–12 (2005).
  Medline CASGoogle Scholar
• 62. Lin Y-K, Huang Z-R, Zhuo R-Z, Fang J-Y. Combination of calcipotriol and methotrexate in nanostructured lipid carriers for topical delivery. Int. J. Nanomed. 5, 117–128 (2010).
  Medline CASGoogle Scholar
• 63. Negi P, Sharma I, Hemrajani C et al. Thymoquinone-loaded lipid vesicles: a promising nanomedicine for psoriasis. BMC Complement. Altern. Med. 19(1), 1–9 (2019).
  MedlineGoogle Scholar
• 64. Vasanth S, Dubey A, Ravi GS et al. Development and investigation of vitamin C-enriched adapalene-loaded transfersome gel: a collegial approach for the treatment of acne vulgaris. AAPS PharmSciTech 21, 1–17 (2020).
  Google Scholar
• 65. Cristiano MC, Froiio F, Mancuso A et al. In vitro and in vivo trans-epidermal water loss evaluation following topical drug delivery systems application for pharmaceutical analysis. J. Pharm. Biomed. Anal. 186, doi:10.1016/j.jpba.2020.113295 (2020) (Epub ahead of print).
  MedlineGoogle Scholar
• 66. Marks R. Acne and its management beyond the age of 35 years. Am. J. Clin. Dermatol. 5, 459–462 (2004).
  MedlineGoogle Scholar
• 67. del Pulgar JIGP, Nebreda RF, García JML, Cunliffe WJ. Resistencia antibiótica del Propionibacterium acnes en pacientes tratados por acné vulgar en Málaga. Actas Dermosifiliogr. 93(4), 271–275 (2002).
  Google Scholar
• 68. Nouh AH, Elshahid AR, Kadah AS, Zeyada YA. Topical niacinamide (nicotinamide) treatment for discoid lupus erythematosus (DLE): a prospective pilot study. J. Cosmet. Dermatol. 22(5), 1647–1657 (2023).
  MedlineGoogle Scholar
• 69. Xu H, Li H. Acne, the skin microbiome, and antibiotic treatment. Am. J. Clin. Dermatol. 20(3), 335–344 (2019).
  MedlineGoogle Scholar
• 70. Shaw JC, White LE. Persistent acne in adult women. Arch. Dermatol. 137(9), 1252–1253 (2001).
  Medline CASGoogle Scholar
• 71. Elsaie ML. Hormonal treatment of acne vulgaris: an update. Clin. Cosmet. Investig. Dermatol. 9, 241–248 (2016).
  Medline CASGoogle Scholar
• 72. Harper JC. Use of oral contraceptives for management of acne vulgaris: practical considerations in real world practice. Dermatol. Clin. 34(2), 159–165 (2016).
  Medline CASGoogle Scholar
• 73. Williams C, Layton AM. Persistent acne in women: implications for the patient and for therapy. Am. J. Clin. Dermatol. 7, 281–290 (2006).
  MedlineGoogle Scholar
• 74. Bettoli V, Guerra-Tapia A, Herane MI, Piquero-Martín J. Challenges and solutions in oral isotretinoin in acne: reflections on 35 years of experience. Clin. Cosmet. Investig. Dermatol. 12, 943–951 (2019).
  Medline CASGoogle Scholar
• 75. Landis MN. Optimizing isotretinoin treatment of acne: update on current recommendations for monitoring, dosing, safety, adverse effects, compliance, and outcomes. Am. J. Clin. Dermatol. 21(3), 411–419 (2020).
  MedlineGoogle Scholar
• 76. Grace R. Cosmeceuticals: functional food for the skin. Natural Foods Merchandiser 23, 92–99 (2002).
  Google Scholar
• 77. Goulden V, Clark SM, McGeown C, Cunliffe WJ. Treatment of acne with intermittent isotretinoin. Br. J. Dermatol. 137(1), 106–108 (1997).
  Medline CASGoogle Scholar
• 78. Karsai S, Schmitt L, Raulin C. The pulsed-dye laser as an adjuvant treatment modality in acne vulgaris: a randomized controlled single-blinded trial. Br. J. Dermatol. 163(2), 395–401 (2010).
  Medline CASGoogle Scholar
• 79. Mason J, Mason A, Cork M. Topical preparations for the treatment of psoriasis: a systematic review. Br. J. Dermatol. 146(3), 351–364 (2002).
  Medline CASGoogle Scholar
• 80. Bruner CR, Feldman SR, Ventrapragada M, Fleischer AB Jr. A systematic review of adverse effects associated with topical treatments for psoriasis. Dermatol. Online J. 9(1), 2 (2003).
  MedlineGoogle Scholar
• 81. Fitzpatrick TB. The validity and practicality of sun-reactive skin types I through VI. Arch. Dermatol. 124(6), 869–871 (1988).
  Medline CASGoogle Scholar
• 82. Stern RS. Genital tumors among men with psoriasis exposed to psoralens and ultraviolet A radiation (PUVA) and ultraviolet B radiation. The Photochemotherapy Follow-up Study. N. Engl. J. Med. 322(16), 1093–1097 (1990).
  Medline CASGoogle Scholar
• 83. Coven TR, Burack LH, Gilleaudeau P, Keogh M, Ozawa M, Krueger JG. Narrowband UV-B produces superior clinical and histopathological resolution of moderate-to-severe psoriasis in patients compared with broadband UV-B2. Arch. Dermatol. 133(12), 1514–1522 (1997).
  Medline CASGoogle Scholar
• 84. Cameron H, Dawe R, Yule S, Murphy J, Ibbotson S, Ferguson J. A randomized, observer-blinded trial of twice vs. three times weekly narrowband ultraviolet B phototherapy for chronic plaque psoriasis. Br. J. Dermatol. 147(5), 973–978 (2002).
  Medline CASGoogle Scholar
• 85. Singh M, Suman S, Shukla Y. New enlightenment of skin cancer chemoprevention through phytochemicals: in vitro and in vivo studies and the underlying mechanisms. Biomed. Res. Int. 2014, doi:10.1155/2014/243452 (2014) (Epub ahead of print).
  Google Scholar
• 86. Lapolla W, Yentzer BA, Bagel J, Halvorson CR, Feldman SR. A review of phototherapy protocols for psoriasis treatment. J. Am. Acad. Dermatol. 64(5), 936–949 (2011).
  MedlineGoogle Scholar
• 87. Dogra S, Mahajan R. Phototherapy for atopic dermatitis. Indian J. Dermatol. Venereol. Leprol. 81, 10 (2015).
  MedlineGoogle Scholar
• 88. Eichenfield LF, Tom WL, Chamlin SL et al. Guidelines of care for the management of atopic dermatitis: section 1. Diagnosis and assessment of atopic dermatitis. J. Am. Acad. Dermatol. 70(2), 338–351 (2014).
  MedlineGoogle Scholar
• 89. Vangipuram R, Feldman S. Ultraviolet phototherapy for cutaneous diseases: a concise review. Oral Dis. 22(4), 253–259 (2016).
  Medline CASGoogle Scholar
• 90. Schaarschmidt M-L, Kromer C, Herr R, Schmieder A, Goerdt S, Peitsch WK. Treatment satisfaction of patients with psoriasis. Acta Derm. Venereol. 95(5), 572–578 (2015).
  MedlineGoogle Scholar
• 91. Aramwit P, Fongsodsri K, Tuentam K et al. Sericin coated thin polymeric films reduce keratinocyte proliferation via the mTOR pathway and epidermal inflammation through IL17 signaling in psoriasis rat model. Sci. Rep. 13(1), (2023) (Epub ahead of print).
  Google Scholar
• 92. Naldi L, Griffiths C. Traditional therapies in the management of moderate to severe chronic plaque psoriasis: an assessment of the benefits and risks. Br. J. Dermatol. 152(4), 597–615 (2005).
  Medline CASGoogle Scholar
• 93. van de Kerkhof PCM, Kragballe K, Segaert S, Lebwohl M, Council IP. Factors impacting the combination of topical corticosteroid therapies for psoriasis: perspectives from the international psoriasis council. J. Eur. Acad. Dermatol. Venereol. 25(10), 1130–1139 (2011).
  MedlineGoogle Scholar
• 94. Tan X, Feldman SR, Chang J, Balkrishnan R. Topical drug delivery systems in dermatology: a review of patient adherence issues. Expert Opin. Drug Deliv. 9(10), 1263–1271 (2012).
  Medline CASGoogle Scholar
• 95. Bazin R, Fanchon C. Equivalence of face and volar forearm for the testing of moisturizing and firming effect of cosmetics in hydration and biomechanical studies. Int. J. Cosmet. Sci. 28(6), 453–461 (2006).
  Medline CASGoogle Scholar
• 96. Daniels R, Knie U. Galenics of dermal products – vehicles, properties and drug release. JDDG 5(5), 367–383 (2007).
  Google Scholar
• 97. Wiechers J, Barlow T. Skin moisturisation and elasticity originate from at least two different mechanisms. Int. J. Cosmet. Sci. 21(6), 425–435 (1999).
  Medline CASGoogle Scholar
• 98. Arif T. Salicylic acid as a peeling agent: a comprehensive review. Clin. Cosmet. Investig. Dermatol. 8, 455–461 (2015).
  Medline CASGoogle Scholar
• 99. Huang J, Weinstein SJ, Yu K et al. Association between serum retinol and overall and cause-specific mortality in a 30-year prospective cohort study. Nat. Commun. 21(1), 6418 (2021).
  Google Scholar
• 100. Nurzyńska-Wierdak R, Pietrasik D, Walasek-Janusz M. Essential oils in the treatment of various types of acne – a review. Plants 12(1), 90 (2023).
  CASGoogle Scholar
• 101. Fitton A, Goa KL. Azelaic acid. Drugs 41, 780–798 (1991).
  Medline CASGoogle Scholar
• 102. Li F, Chen H, Chen D et al. Clinical evidence of the efficacy and safety of a new multi-peptide anti-aging topical eye serum. J. Cosmet. Dermatol. doi:10.1111/jocd.15849 (2023) (Epub ahead of print). • Peptides recently gain significant attention due to antimicrobial property thus incorporating them within nanocarriers could be potential mode of delivering topically and treating dermal complications.
  Google Scholar
• 103. Casari A, Al Sibai R, Mediani M, Molinari M, Fiore W. Evaluation of a novel topical formulation for the treatment of problematic skin: results of an Italian clinical study. J. Dermatol. Res. Ther. 8(1), 115 (2022).
  Google Scholar
• 104. Patwekar S, Gattani S, Giri R, Bade A, Sangewar B, Raut V. Review on nanoparticles used in cosmetics and dermal products. World J. Pharm. Pharm. Sci. 3, 1407–1421 (2014).
  CASGoogle Scholar
• 105. Bangale M, Mitkare S, Gattani S, Sakarkar D. Recent nanotechnological aspects in cosmetics and dermatological preparations. Int. J. Pharm. Pharm. Sci. 4(2), 88–97 (2012).
  CASGoogle Scholar
• 106. Oliveira C, Coelho C, Teixeira JA, Ferreira-Santos P, Botelho CM. Nanocarriers as active ingredients enhancers in the cosmetic industry – the European and North America regulation challenges. Molecules 27(5), 1–35(2022).
  Google Scholar
• 107. Zhou H, Luo D, Chen D et al. Current advances of nanocarrier technology-based active cosmetic ingredients for beauty applications. Clin. Costmet. Investig. Dermatol. 14, 867–887 (2021).
  Medline CASGoogle Scholar
• 108. Pourmand A, Abdollahi M. Current opinion on nanotoxicology. Daru 20(1), 1–3 (2012).
  MedlineGoogle Scholar
• 109. Mostafalou S, Mohammadi H, Ramazani A, Abdollahi M. Different biokinetics of nanomedicines linking to their toxicity; an overview. DARU J. Pharm. Sci. 21, 1–4 (2013).
  Google Scholar
• 110. Wang S, Su R, Nie S et al. Application of nanotechnology in improving bioavailability and bioactivity of diet-derived phytochemicals. J. Nutr. Biochem. 25(4), 363–376 (2014).
  Medline CASGoogle Scholar
• 111. Chermahini SH, Majid FA, Sarmidi MR. Cosmeceutical value of herbal extracts as natural ingredients and novel technologies in anti-aging. J. Med. Plant Res. 5(14), 3074–3077 (2011).
  CASGoogle Scholar
• 112. Müller RH, Shegokar R, Keck CM. 20 years of lipid nanoparticles (SLN and NLC): present state of development and industrial applications. Cur. Drug Discov. Technol. 8(3), 207–227 (2011).
  Medline CASGoogle Scholar
• 113. Jimtaisong A, Saewan N. Utilization of carboxymethyl chitosan in cosmetics. Int. J. Cosmet. Sci. 36(1), 12–21 (2014).
  Medline CASGoogle Scholar
• 114. Borowska S, Brzóska MM. Metals in cosmetics: implications for human health. J. Appl. Toxicol. 35(6), 551–572 (2015).
  Medline CASGoogle Scholar
• 115. Szmyd R, Goralczyk AG, Skalniak L et al. Effect of silver nanoparticles on human primary keratinocytes. Biol. Chem. 394(1), 113–123 (2013).
  Medline CASGoogle Scholar
• 116. Tucci P, Porta G, Agostini M et al. Metabolic effects of TiO₂ nanoparticles, a common component of sunscreens and cosmetics, on human keratinocytes. Cell Death Dis. 4(3), 1–11 (2013).
  Google Scholar
• 117. Hackenberg S, Kleinsasser N. Dermal toxicity of ZnO nanoparticles: a worrying feature of sunscreen? Nanomedicine 7(4), 461–463 (2012).
  CASGoogle Scholar
• 118. Singh S, Chunglok W, Nwabor OF, Ushir YV, Singh S, Panpipat W. Hydrophilic biopolymer matrix antibacterial peel-off facial mask functionalized with biogenic nanostructured material for cosmeceutical applications. J. Polym. Environ. 30(3), 938–953 (2022).
  CASGoogle Scholar
• 119. Qi Y, Wei S, Xin T et al. Passage of exogeneous fine particles from the lung into the brain in humans and animals. Proc. Natl Acad. Sci. USA 119(26), e2117083119 (2022).
  Medline CASGoogle Scholar
• 120. Mavon A, Miquel C, Lejeune O, Payre B, Moretto P. In vitro percutaneous absorption and in vivo stratum corneum distribution of an organic and a mineral sunscreen. Skin Pharmacol. Physiol. 20(1), 10–20 (2007).
  Medline CASGoogle Scholar
• 121. Mofazzal Jahromi MA, Sahandi Zangabad P, Moosavi Basri SM et al. Nanomedicine and advanced technologies for burns: preventing infection and facilitating wound healing. Adv. Drug Deliv. Rev. 123, 33–64 (2018).
  MedlineGoogle Scholar
• 122. Chen J, Dong X, Zhao J, Tang G. In vivo acute toxicity of titanium dioxide nanoparticles to mice after intraperitioneal injection. J. Appl. Toxicol. 29(4), 330–337 (2009). •• Although metallic nanoparticles demonstrate excellent efficacy due to their size and specific shape, however the toxicity concern are important considering drug and cosmetic act. Therefore considering safety and efficacy of product before use by consumer biocompatibility of cosmetics is deemed necessary.
  Medline CASGoogle Scholar
• 123. Sajid M, Ilyas M, Basheer C et al. Impact of nanoparticles on human and environment: review of toxicity factors, exposures, control strategies, and future prospects. Environ. Sci. Pollution Res. 22, 4122–4143 (2015).
  MedlineGoogle Scholar
• 124. Abbasi BH, Fazal H, Ahmad N, Ali M, Giglioli-Guivarch N, Hano C. Nanomaterials for cosmeceuticals: nanomaterials-induced advancement in cosmetics, challenges, and opportunities. In: Nanocosmetics. Nanda ANanda SNguyen TARajendran SSlimani Y (Eds). Elsevier, MA, USA, 79–108 (2020).
  Google Scholar
• 125. Raj S, Jose S, Sumod U, Sabitha M. Nanotechnology in cosmetics: opportunities and challenges. J. Pharm. Bioallied Sci. 4(3), 186 (2012).
  MedlineGoogle Scholar
• 126. Demir N. Nanotechnology in cosmetics: opportunities and challenges. NanoEra 1(1), 19–23 (2021).
  Google Scholar
• 127. Schwarz JC, Baisaeng N, Hoppel M, Löw M, Keck CM, Valenta C. Ultra-small NLC for improved dermal delivery of coenyzme Q10. Int. J. Pharm. 447(1–2), 213–217 (2013).
  Medline CASGoogle Scholar
• 128. Beyer RE, Burnett B-A, Cartwright KJ et al. Tissue coenzyme Q (ubiquinone) and protein concentrations over the life span of the laboratory rat. Mech. Ageing Dev. 32(2–3), 267–281 (1985).
  Medline CASGoogle Scholar
• 129. Amnuaikit T, Shankar R, Benjakul S. Hydrolyzed fish collagen serum from by-product of food industry: cosmetic product formulation and facial skin evaluation. Sustainability 14(24), (2022) (Epub ahead of print).
  Google Scholar
• 130. Mursyid AM, Waris R. Formulation and evaluation of pharmaceutical stable serum of Duchesnea indica (arbenan). Univ. J. Pharm. Res. 6(1), 38–42 (2021).
  CASGoogle Scholar
• 131. Kwak M-S, Ahn H-J, Song K-W. Rheological investigation of body cream and body lotion in actual application conditions. Korea–Australia Rheol. J. 27, 241–251 (2015).
  Google Scholar
• 132. Dayan N. (Ed.). Handbook of Formulating Dermal Applications: a Definitive Practical Guide. John Wiley & Sons, Toronto, Canada (2016).
  Google Scholar
• 133. Sasidharan S, Joseph P, Junise. Formulation and evaluation of fairness serum using polyherbal extracts. Int. J. Pharm. 4(3), 105–112 (2014).
  Google Scholar
• 134. Stewart S, Parker M, Amézquita A, Pitt T. Microbiological risk assessment for personal care products. Int. J. Cosmet. Sci. 38(6), 634–645 (2016).
  Medline CASGoogle Scholar
• 135. Thakre AD. Formulation and development of de pigment serum incorporating fruits extract. Int. J. Innov. Sci. Res. Technol. 2(12), 330–382 (2017).
  Google Scholar
• 136. Jagtap PP, Chaudhari VA, Davar RN, Patil NC, Joshi PP, Desale BR. Formulation and development of anti-acne serum using Euphorbia hirta. Int. J. All Res. Writings 2(12), 171–179 (2020).
  Google Scholar
• 137. Robinson M, Cohen C, de Fraissinette Ade B, Ponec M, Whittle E, Fentem J. Non-animal testing strategies for assessment of the skin corrosion and skin irritation potential of ingredients and finished products. Food Chem. Toxicol. 40(5), 573–592 (2002).
  Medline CASGoogle Scholar
• 138. Matarrese P, Beauchef G, Peno-Mazzarino L, Lati E, Fitoussi R, Vié K. Assessment of an ex vivo irritation test performed on human skin explants and comparison of its results with those of a 24-/48-h human patch test for the evaluation of cosmetics. Toxicology In Vitro 70, doi:10.1016/j.tiv.2020.105030 (2021) (Epub ahead of print).
  Google Scholar
• 139. Amnuaikit T, Khakhong S, Khongkow P. Formulation development and facial skin evaluation of serum containing jellose from tamarind seeds. J. Pharm. Res. Int. 1, 14 (2019).
  Google Scholar
• 140. Clarys P, Barel AO, Gabard B. Non-invasive electrical measurements for the evaluation of the hydration state of the skin: comparison between three conventional instruments – the Comeometer^®, the Skicon^® and the Nova DPM^®. Skin Res. Technol. 5(1), 14–20 (1999).
  Google Scholar
• 141. Ribeiro RC, Barreto SM, Ostrosky EA, Rocha-Filho PA, Veríssimo LM, Ferrari M. Production and characterization of cosmetic nanoemulsions containing Opuntia ficus-indica (L.) mill extract as moisturizing agent. Molecules 20(2), 2492–2509 (2015).
  MedlineGoogle Scholar
• 142. Greenhall AM. House bat management. Resource Pub. 143, 78 (1982).
  Google Scholar
• 143. Clarys P, Alewaeters K, Lambrecht R, Barel A. Skin color measurements: comparison between three instruments: the Chromameter^®, the DermaSpectrometer^® and the Mexameter^®. Skin Res. Technol. 6(4), 230–238 (2000).
  MedlineGoogle Scholar
• 144. Rossi D, Realdon N. Surface tensiometry approach to characterize cosmetic products in the beauty sector. In: Surface Science and Adhesion in Cosmetics. Mittal KLBui HS (Eds). Scrivener Publishing LLC, MA, USA 309–352 (2021).
  Google Scholar
• 145. Tatmatsu-Rocha JC, Ferraresi C, Hamblin MR et al. Low-level laser therapy (904 nm) can increase collagen and reduce oxidative and nitrosative stress in diabetic wounded mouse skin. J. Photochem. Photobiol. B. 164, 96–102 (2016).
  Medline CASGoogle Scholar
• 146. Nammour S, El Mobadder M, Namour M et al. Aesthetic treatment outcomes of capillary hemangioma, venous lake, and venous malformation of the lip using different surgical procedures and laser wavelengths (Nd: YAG, Er, Cr: YSGG, CO2, and Diode 980 nm). Int. J. Environ. Res. Public Health 17(22), 8665 (2020).
  Medline CASGoogle Scholar
• 147. Suter F, Schmid D, Wandrey F, Zülli F. Heptapeptide-loaded solid lipid nanoparticles for cosmetic anti-aging applications. Eur. J. Pharm. Biopharm. 108, 304–309 (2016).
  Medline CASGoogle Scholar
• 148. Ramezanli T, Zhang Z, Michniak-Kohn BB. Development and characterization of polymeric nanoparticle-based formulation of adapalene for topical acne therapy. Nanomedicine 13(1), 143–152 (2017).
  Medline CASGoogle Scholar
• 149. Amasya G, Ozturk C, Aksu B, Tarimci N. QbD based formulation optimization of semi-solid lipid nanoparticles as nano-cosmeceuticals. J. Drug Deliv. Sci. Technol. 66, doi:10.1016/j.jddst.2021.102737 (2021) (Epub ahead of print).
  Google Scholar
• 150. Khotimah H, Lestari Ismail DD, Widasmara D et al. Ameliorative effect of gel combination of Centella asiatica extract transfersomes and rosemary essential oil nanoemulsion against UVB-induced skin aging in Balb/c mice. F1000Research 11(288), 1–21 (2022).
  Google Scholar
• 151. Kapoor MS, D'Souza A, Aibani N et al. Stable liposome in cosmetic platforms for transdermal folic acid delivery for fortification and treatment of micronutrient deficiencies. Sci. Rep. 8(1), (2018) (Epub ahead of print).
  Google Scholar
• 152. Moccia F, Liberti D, Giovando S et al. Chestnut wood mud as a source of ellagic acid for dermo-cosmetic applications. Antioxidants 11(9), 1681 (2022).
  Medline CASGoogle Scholar
• 153. Avadhani KS, Manikkath J, Tiwari M et al. Skin delivery of epigallocatechin-3-gallate (EGCG) and hyaluronic acid loaded nano-transfersomes for antioxidant and anti-aging effects in UV radiation induced skin damage. Drug Deliv. 24(1), 61–74 (2017).
  Medline CASGoogle Scholar
• 154. Kanlayavattanakul M, Lourith N, Ospondpant D, Ruktanonchai U, Pongpunyayuen S, Chansriniyom C. Salak plum peel extract as a safe and efficient antioxidant appraisal for cosmetics. Biosci. Biotechnol. Biochem. 77(5), 1068–1074 (2013).
  Medline CASGoogle Scholar
• 155. Nwabor OF, Singh S. A systematic review on Rhodomyrtus tomentosa (Aiton) Hassk: a potential source of pharmacological relevant bioactive compounds with prospects as alternative remedies in varied medical conditions. IJPSN 15(2), 5875–5891 (2022).
  Google Scholar
• 156. Chorachoo J, Amnuaikit T, Voravuthikunchai SP. Liposomal encapsulated rhodomyrtone: a novel antiacne drug. Evid. Based Complement. Alternat. Med. 2013, doi:10.1155/2013/157635 (2013) (Epub ahead of print). • Similar to bioresource-derived compound the synthetic compound demonstrate efficacy against psoriasis and acne when incorporated within lipid vesicles. Hence nanocarrier containing such compounds are outmost important too.
  MedlineGoogle Scholar
• 157. Burlando B, Verotta L, Cornara L, Bottini-Massa E. Herbal Principles in Cosmetics: Properties and Mechanisms of Action. CRC Press, FL, USA (2010).
  Google Scholar
• 158. Guo F, Lin M, Gu Y, Zhao X, Hu G. Preparation of PEG-modified proanthocyanidin liposome and its application in cosmetics. Eur. Food Res. Technol. 240, 1013–1021 (2015).
  CASGoogle Scholar
• 159. Kaur CD, Saraf S. Topical vesicular formulations of Curcuma longa extract on recuperating the ultraviolet radiation–damaged skin. J. Cosmet. Dermatol. 10(4), 260–265 (2011).
  MedlineGoogle Scholar
• 160. Saraf S, Jeswani G, Kaur CD, Saraf S. Development of novel herbal cosmetic cream with Curcuma longa extract loaded transfersomes for antiwrinkle effect. Afr. J. Pharm. Pharmacol. 5(8), 1054–1062 (2011). •• Considering age related issue such as wrinkle over face are serious problem among the current generation people. The incorporation of herbal extract within the nanocarriers are potential option for treating wrinkles and use as a cosmetics.
  Google Scholar
• 161. Bowman DM, May ND, Maynard AD. Nanomaterials in cosmetics: regulatory aspects. In: Analysis of Cosmetic Products. Salvador AChisvert A (Eds). Elsevier, London UK, 289–302 (2018).
  Google Scholar
• 162. Katz LM, Dewan K, Bronaugh RL. Nanotechnology in cosmetics. Food Chem. Toxicol. 85, 127–137 (2015).
  Medline CASGoogle Scholar
• 163. Adams DJ. The valley of death in anticancer drug development: a reassessment. Trends Pharmacol. Sci. 33(4), 173–180 (2012).
  Medline CASGoogle Scholar
• 164. Farjadian F, Ghasemi A, Gohari O, Roointan A, Karimi M, Hamblin MR. Nanopharmaceuticals and nanomedicines currently on the market: challenges and opportunities. Nanomedicine (Lond.) 14(1), 93–126 (2019).
  CASGoogle Scholar