References
- 1. Tissue-specific relaxin-2 is differentially associated with the presence/size of an arterial aneurysm and the severity of atherosclerotic disease in humans. Acta Pharmacol. Sin.
doi:10.1038/s41401-019-0350-5 (2020) (Epub ahead of print). - 2. Antiinflammatory therapy with canakinumab for atherosclerotic disease. N. Engl. J. Med. 377(12), 1119–1131 (2017).
- 3. . Relationship of C-reactive protein reduction to cardiovascular event reduction following treatment with canakinumab: a secondary analysis from the CANTOS randomised controlled trial. Lancet 391(10118), 319–328 (2018).
- 4. Inhibition of interleukin-1beta by canakinumab and cardiovascular outcomes in patients with chronic kidney disease. J. Am. Coll. Cardiol. 71(21), 2405–2414 (2018).
- 5. Insight into tubulin regulation from a complex with colchicine and a stathmin-like domain. Nature 428(6979), 198–202 (2004).
- 6. . Low-dose colchicine for secondary prevention of cardiovascular disease. J. Am. Coll. Cardiol. 61(4), 404–410 (2013).
- 7. Efficacy and safety of low-dose colchicine after myocardial infarction. N. Engl. J. Med. 381(26), 2497–2505 (2019).
- 8. Clonal hematopoiesis associated with TET2 deficiency accelerates atherosclerosis development in mice. Science 355(6327), 842–847 (2017).
- 9. Expression of interleukin-18 in human atherosclerotic plaques and relation to plaque instability. Circulation 104(14), 1598–1603 (2001).
- 10. . Anti-inflammatory effects of statins: clinical evidence and basic mechanisms. Nat. Rev. Drug Discov. 4(12), 977–987 (2005).
- 11. . Statins and the endothelium. Vascul. Pharmacol. 46(1), 1–9 (2007).
- 12. . 15-epi-lipoxin A4-mediated induction of nitric oxide explains how aspirin inhibits acute inflammation. J. Exp. Med. 200(1), 69–78 (2004).
- 13. . Aspirin-dependent platelet inflammatory inhibition in healthy subjects decreases NLRP-1 inflammasome. Ann. Vasc. Surg. 59, 244–247 (2019).
- 14. . Inflammation, aspirin, and the risk of cardiovascular disease in apparently healthy men. N. Engl. J. Med. 336(14), 973–979 (1997).
- 15. . Effect of P2Y12 inhibitors on inflammation and immunity. Thromb. Haemost. 114(3), 490–497 (2015).
- 16. Ticagrelor versus clopidogrel in patients with acute coronary syndromes. N. Engl. J. Med. 361(11), 1045–1057 (2009).
- 17. Low-dose methotrexate for the prevention of atherosclerotic events. N. Engl. J. Med. 380(8), 752–762 (2019).
- 18. Effects of succinobucol (AGI-1067) after an acute coronary syndrome: a randomised, double-blind, placebo-controlled trial. Lancet 371(9626), 1761–1768 (2008).
- 19. Varespladib and cardiovascular events in patients with an acute coronary syndrome: the VISTA-16 randomized clinical trial. JAMA 311(3), 252–262 (2014).
- 20. Effect of darapladib on major coronary events after an acute coronary syndrome: the SOLID-TIMI 52 randomized clinical trial. JAMA 312(10), 1006–1015 (2014).
- 21. Effects of the P-selectin antagonist inclacumab on myocardial damage after percutaneous coronary intervention for non-ST-segment elevation myocardial infarction: results of the SELECT-ACS trial. J. Am. Coll. Cardiol. 61(20), 2048–2055 (2013).
- 22. Effects of interleukin-1 blockade with anakinra on adverse cardiac remodeling and heart failure after acute myocardial infarction [from the Virginia Commonwealth University-Anakinra Remodeling Trial (2) (VCU-ART2) pilot study]. Am. J. Cardiol. 111(10), 1394–1400 (2013).
- 23. . A randomized Phase II study of Xilonix, a targeted therapy against interleukin 1alpha, for the prevention of superficial femoral artery restenosis after percutaneous revascularization. J. Vasc. Surg. 63(1), 133–141.e1 (2016).
- 24. A Phase II randomized, double-blind, placebo-controlled study of the effect of VIA-2291, a 5-lipoxygenase inhibitor, on vascular inflammation in patients after an acute coronary syndrome. Atherosclerosis 240(1), 53–60 (2015).
- 25. Effect of losmapimod on cardiovascular outcomes in patients hospitalized with acute myocardial infarction: a randomized clinical trial. JAMA 315(15), 1591–1599 (2016).