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From part to whole, operative link on to endoscopic grading of gastric intestinal metaplasia, pathology to endoscopy: gastric intestinal metaplasia graded by endoscopy

    Ning Wei

    Medical School of Southeast University, Nanjing, 210009, China

    Department of Gastroenterology, Southeast University Affiliated Zhongda Hospital, Nanjing, 210009, China

    ‡Authors contributed equally

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    ,
    Mengyue Zhou

    Medical School of Southeast University, Nanjing, 210009, China

    Department of Gastroenterology, Southeast University Affiliated Zhongda Hospital, Nanjing, 210009, China

    ‡Authors contributed equally

    Search for more papers by this author

    ,
    Siyu Lei

    Medical School of Southeast University, Nanjing, 210009, China

    Department of Gastroenterology, Southeast University Affiliated Zhongda Hospital, Nanjing, 210009, China

    ‡Authors contributed equally

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    ,
    Ling Yang

    Medical School of Southeast University, Nanjing, 210009, China

    Department of Gastroenterology, Southeast University Affiliated Zhongda Hospital, Nanjing, 210009, China

    ,
    Zhihong Duan

    Medical School of Southeast University, Nanjing, 210009, China

    Department of Gastroenterology, Southeast University Affiliated Zhongda Hospital, Nanjing, 210009, China

    ,
    Youyu Zhang

    Medical School of Southeast University, Nanjing, 210009, China

    Department of Gastroenterology, Southeast University Affiliated Zhongda Hospital, Nanjing, 210009, China

    ,
    Zhiheng Zhong

    Medical School of Southeast University, Nanjing, 210009, China

    Department of Gastroenterology, Southeast University Affiliated Zhongda Hospital, Nanjing, 210009, China

    ,
    Yang Liu

    Department of Gastroenterology, Southeast University Affiliated Zhongda Hospital, Nanjing, 210009, China

    &
    Ruihua Shi

    *Author for correspondence: Tel.: +86 139 5179 9326;

    E-mail Address: ruihuashi@126.com

    Medical School of Southeast University, Nanjing, 210009, China

    Department of Gastroenterology, Southeast University Affiliated Zhongda Hospital, Nanjing, 210009, China

    Published Online:https://doi.org/10.2217/fon-2021-1390

    Objective: To conduct a systematic review and meta-analysis on the prediction of severity of gastric intestinal metaplasia (GIM) in localized and entire gastric mucosa using endoscopy. Methods: The authors searched Web of Science, PubMed, Embase and Cochrane Central Register of Controlled Trials and performed systematic searches on endoscopic grading of GIM of the entire stomach using Meta-DiSc and Stata. Results: Sensitivity and specificity for the stratified prediction of overall GIM were 0.91 (95% CI: 0.85–0.95) and 0.91 (95% CI: 0.88–0.93), respectively. Sensitivity in predicting the different grades of GIM was higher in operative link on GIM assessment grades 0, III and IV but lower in grades I and II. Conclusion: Digital chromoendoscopy is well suited to predicting the severity of localized and overall GIM.

    Papers of special note have been highlighted as: •• of considerable interest

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