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No obvious association exists between mean platelet volume and hypertension subtypes

    Tingwei Li

    Department of Nuclear Medicine, Tianjin Medical University General Hospital, Tianjin, 300052, PR China

    ,
    Zhaowei Meng

    **Author for correspondence: Tel.: +86 186 2203 5159;

    E-mail Address: zmeng@tmu.edu.cn

    Department of Nuclear Medicine, Tianjin Medical University General Hospital, Tianjin, 300052, PR China

    ,
    Wenjuan Zhang

    Department of Cardiology, Tianjin Medical University General Hospital, Tianjin, 300052, PR China

    ,
    Yongle Li

    Department of Cardiology, Tianjin Medical University General Hospital, Tianjin, 300052, PR China

    ,
    Xuefang Yu

    Department of Cardiology, Tianjin Medical University General Hospital, Tianjin, 300052, PR China

    ,
    Xin Du

    Department of Cardiology, Tianjin Medical University General Hospital, Tianjin, 300052, PR China

    ,
    Ming Liu

    Department of Endocrinology & Metabolism, Tianjin Medical University General Hospital, Tianjin, 300052, PR China

    ,
    Qing Zhang

    Department of Health Management, Tianjin Medical University General Hospital, Tianjin, 300052, PR China

    ,
    Ying Gao

    Department of Health Management, Tianjin Medical University General Hospital, Tianjin, 300052, PR China

    ,
    Kun Song

    Department of Health Management, Tianjin Medical University General Hospital, Tianjin, 300052, PR China

    ,
    Xing Wang

    Department of Health Management, Tianjin Medical University General Hospital, Tianjin, 300052, PR China

    &
    Yaguang Fan

    *Author for correspondence: Tel.: +86 131 9466 7199;

    E-mail Address: fanyaguang75@163.com

    Tianjin Key Laboratory of Lung Cancer Metastasis & Tumor Microenvironment, Tianjin Lung Cancer Institute, Tianjin Medical University General Hospital, Tianjin, 300052, PR China

    Published Online:https://doi.org/10.2217/bmm-2020-0305

    Aims: To determine the association between mean platelet volume (MPV) and hypertension subtypes. Participants & results: 44,281 Chinese individuals were enrolled in this cross-sectional study. The mean blood pressure decreased with increasing MPV in females (p = 0.001) and increased MPV seemed to be a potential protective factor for isolated diastolic hypertension in models 1 and 2. The OR (CI) was 0.878 (0.789–0.976) for model 1 and 0.880 (0.789–0.981) for model 2 in males and 0.646 (0.495–0.841) for model 1 and 0.657 (0.503–0.858) for model 2 in females, when MPV was analyzed as a categorical variable. The OR (CI) was 0.947 (0.911–0.985) for Model 1 and 0.947 (0.910–0.985) for Model 2 in males, and 0.886 (0.807–0.973) for Model 1 and 0.892 (0.813–0.978) for Model 2 in females when MPV was analyzed as a continuous variable. However, the statistical difference of OR disappeared when we added blood-related covariates in Model 3. Conclusion: No obvious association exists between MPV and hypertension subtypes. Other blood parameters might have a greater impact on hypertension subtypes.

    Papers of special note have been highlighted as: • of interest; •• of considerable interest

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