Review

Exercise-based cardiac rehabilitation in patients with coronary heart disease: meta-analysis outcomes revisited

Neil Oldridge

University of Wisconsin School of Medicine & Public Health, Aurora Cardiovascular Services, Aurora Medical Group, 6975 N Elm Tree Rd, Glendale, Milwaukee, WI 53217, USA.

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Email the corresponding author at neilb@uwm.edu

Published Online:26 Sep 2012https://doi.org/10.2217/fca.12.34

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Abstract

Cardiac rehabilitation that includes either exercise training alone or exercise training in addition to psychosocial, risk factor management and/or educational interventions is considered a Class I indication [i.e., useful and effective] for patients with coronary heart disease. This overview of six independent cardiac rehabilitation meta-analyses published since 2000 includes a total of 71 randomized clinical trials (n = 13,824 patients) and clearly demonstrates significant clinical outcomes (reduced all-cause and cardiac mortality, nonfatal reinfarction and reduced hospitalization rates) and significant positive changes in modifiable risk factors (total cholesterol, triglycerides and systolic blood pressure). Despite the observation that the elderly, females, minority ethnic groups, low socioeconomic status patients and patients with comorbidities have not been well represented in the randomized clinical trials. Recent guidelines in the UK and USA have concluded with the recommendation that cardiac rehabilitation is reasonable and necessary and should be promoted by healthcare professionals, including senior medical staff.

Keywords:

Papers of special note have been highlighted as: ▪ of interest ▪▪ of considerable interest

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The author has no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.

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