Future Microbiology

Aim: To investigate the role of Candida albicans TUP1-mediated filamentation in the colonization of the mice gut. Materials & methods: We used molecular genetics to generate a strain where filamentation is regulated by altering the expression of the TUP1 ...

Aim: To investigate the direct effect of antibiotics on growth and virulence of the major Candida species associated with invasive infections. Materials & methods: Cefepime, imipenem, meropenem, amoxicillin and vancomycin were tested at twofold the peak ...

Aim: Evaluating carvacrol, derivatives and carvacrol plus anti-TB (anti-tuberculous) drug combination activities in Mycobacterium tuberculosis as well as carvacrol cytotoxicity, efflux pump inhibitor activity and morphological changes in M. tuberculosis ...

Aim: Antimicrobial stewardship programs (ASPs) are urgently needed for Greek hospitals in order to improve antibiotic usage. Patients & methods: An ASP was implemented to a Greek hospital since February 2014. A mandatory order form was introduced for ...

Recently developed 3D noninvasive in vivo optical imaging is providing fresh insights into the understanding of the pathogenesis of invasive bacteria in small animal experimental models. Here, we describe the advantages of 3D diffuse light imaging ...

Nontuberculous mycobacteria (NTM) are environmental organisms that are rapidly emerging as pathogens in the transplant population. The prevalence of infection in transplant recipients remains unknown. While guidelines exist for treatment of NTM, neither ...

Caries and periodontitis are the two most common human dental diseases and are caused by dysbiosis of oral flora. Although commensal microorganisms have been demonstrated to protect against pathogens and promote oral health, most previous studies have ...

Mycobacterioses represent a global health problem and rapid diagnostic improvements are urgently required. Mycobacteria-specific fluorescence and bioluminescence phenomena have been found to be useful for a wide range of mycobacteria-focused research. ...