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Research Article

Economic burden of patients with advanced non-small-cell lung cancer receiving nivolumab versus chemotherapy in China

    Qingqing Chai

    Department of Pharmacy, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai 200000, China

    School of Medicine, Shanghai Jiao Tong University, Shanghai 200000, China

    ,
    Yunjie Shen

    Department of Pharmacy, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai 200000, China

    ,
    Jiangyang Du

    School of Medicine, Shanghai Jiao Tong University, Shanghai 200000, China

    Medical Decision & Economic Group, Department of Pharmacy, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200000, China

    ,
    Jun Zhu

    Department of Pharmacy, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai 200000, China

    &
    Published Online:https://doi.org/10.2217/imt-2020-0030

    Aim: As new treatment patterns are gradually being used in patients with non-small-cell lung cancer, it is necessary to have a better understanding of real-world data on clinical practices and their potential impact on healthcare resource utilization (HCRU). Patients & methods: A retrospective observational study was conducted with electronic medical records from Shanghai Chest Hospital. Hospitalized patients treated with nivolumab or second-line chemotherapy were included. Results: A total of 296 patients were included in this study, of whom 187 were treated with nivolumab. About 74.33% received nivolumab monotherapy at different doses. The mean cost of nivolumab was $3334.14 (±86.69). Nivolumab decreased inpatient days to 1.9545 days with a more stable cost and HCRU per cycle. Conclusion: Nivolumab is expensive but it reduces other HCRU.

    Papers of special note have been highlighted as: • of interest; •• of considerable interest

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