Proper wound healing, including internal and surface tissue regeneration with the minimization of scar formation, is one of the most significant topics in surgical discussions and EpiFix^® dehydrated human amnion/chorion membrane allograft promotes healthy healing.

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References

1. Chouhan D, Dey N, Bhardwaj N, Mandal BB. Emerging and innovative approaches for wound healing and skin regeneration: current status and advances. Biomaterials 216, 119267 (2019).
Medline CASGoogle Scholar
2. Chen J, Lopez CD, Girard AO et al. Dehydrated human amnion/chorion membrane allografts for myelomeningocele and wound reconstruction. Child’s Nerv. Syst. 37(12), 3721–3731 (2021).
MedlineGoogle Scholar
3. Koob TJ, Lim JJ, Massee M, Zabek N, Denoziere G. Properties of dehydrated human amnion/chorion composite grafts: implications for wound repair and soft tissue regeneration. J. Biomed. Mater. Res. B Appl. Biomater. 102(6), 1353–1362 (2014).
MedlineGoogle Scholar
4. Lei J, Priddy LB, Lim JJ, Koob TJ. Dehydrated human amnion/chorion membrane (dHACM) allografts as a therapy for orthopedic tissue repair. Tech. Orthop. 32(3), 149–157 (2017).
Google Scholar
5. Subach BR, Copay AG. The use of a dehydrated amnion/chorion membrane allograft in patients who subsequently undergo re-exploration after posterior lumbar instrumentation. Adv. Orthop. 2015, 501202 (2015).
MedlineGoogle Scholar
6. Shaw KA, Parada SA, Gloystein DM, Devine JG. The science and clinical applications of placental tissues in spine surgery. Global Spine J. 8(6), 629–637 (2018).
MedlineGoogle Scholar
7. Leckie SK, Sowa GA, Bechara BP et al. Injection of human umbilical tissue-derived cells into the nucleus pulposus alters the course of intervertebral disc degeneration in vivo. Spine J. 13(3), 263–272 (2013).
MedlineGoogle Scholar
8. Zhao Y, Tang F, Xiao Z et al. Clinical study of NeuroRegen Scaffold combined with human mesenchymal stem cells for the repair of chronic complete spinal cord injury. Cell Transplant. 26(5), 891–900 (2017).
MedlineGoogle Scholar
9. Papanna R, Moise KJ Jr, Mann LK et al. Cryopreserved human umbilical cord patch for in-utero spina bifida repair. Ultrasound Obstet. Gynecol. 47(2), 168–176 (2016).
Medline CASGoogle Scholar
10. Papanna R, Mann LK, Snowise S et al. Neurological outcomes after human umbilical cord patch for in utero spina bifida repair in a Sheep model. AJP Rep. 6(3), e309–317 (2016).
MedlineGoogle Scholar
11. Choi HJ, Kim KB, Kwon YM. Effect of amniotic membrane to reduce post laminectomy epidural adhesion on a rat model. J. Korean Neurosurg. Soc. 49(6), 323–328 (2011).
MedlineGoogle Scholar

Vol. 17, No. 8

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Received 2 May 2022

Accepted 6 May 2022

Published online 31 May 2022

Published in print August 2022

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Financial & competing interests disclosure

The authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.

No writing assistance was utilized in the production of this manuscript.

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Placental-based allograft use for tissue regeneration and scar prevention for neurosurgical wounds

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