The primary goal of this study was to compile the top 50 most cited articles on the use of platelet-rich plasma (PRP). A search of relevant studies was performed in accordance with the PRISMA guidelines in Web of Science. The top 25 most cited articles in osteoarthritis and tendinopathy were then compiled and evaluated. Level 1 evidence articles constituted the majority of the studies (64%) and were more likely to have a higher citation density. Altmetric data was highest for level 1 systematic reviews. Of the articles that report a positive outcome for PRP, 13% (2/16) had low risk of bias. This study defines the most cited and influential publications regarding PRP to further research in this area.

Plain language summary

Osteoarthritis, which is degeneration of joints from overuse and/or injuries, and tendinopathy, which is usually a chronic injury of the tendons attached to muscles and bones, are big issues in sports medicine. Platelet-rich plasma (PRP), which is a concentrated mixture of platelets from the patient’s own blood, could be an effective treatment for these conditions, but the literature on PRP is limited. This article lists the top 25 most cited articles on the use of PRP in osteoarthritis and in tendinopathy, and it also analyzes how much these articles have been used in research and in public discord. This article is useful as a reading list for physicians, trainees, patients and researchers to know the evidence for PRP.

Tweetable abstract

The top 25 most cited articles on the use of platelet-rich plasma in both osteoarthritis and tendinopathy are listed. This article is useful as a reading list for medical practitioners and researchers.

Keywords:

Papers of special note have been highlighted as: • of interest; •• of considerable interest

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Received 15 February 2022

Accepted 7 April 2022

Published online 17 May 2022

Published in print July 2022

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Author contributions

All authors contributed to the origin of the article idea and to the analysis and interpretation of the data, as well as the drafting, revising and finalizing of the written work, and they agree to be accountable for all aspects of the work. C Cash and L Scott were responsible for data acquisition.

Financial & competing interests disclosure

The authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.

No writing assistance was utilized in the production of this manuscript.

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