References
- 1. . Tissue engineering and regenerative medicine: recent innovations and the transition to translation. Tissue Eng. Part B Rev. 19(1), 1–13 (2013).
- 2. . Tissue engineering and regenerative medicine: concepts for clinical application. Rejuvenation Res. 7(1), 15–31 (2004).
- 3. . Smart biomaterials design for tissue engineering and regenerative medicine. Biomaterials 28(34), 5068–5073 (2007).
- 4. Scaffolding strategies for tissue engineering and regenerative medicine applications. Materials 12(11), 1824 (2019).
- 5. . Exosomal therapy-a new frontier in regenerative medicine. Stem Cell Investig. 8, 7 (2021).
- 6. . Sources, isolation strategies and therapeutic outcome of exosomes at a glance. Regen. Med. 15(12), 2361–2378 (2020).
- 7. . Advances in exosomes derived from different cell sources and cardiovascular diseases. BioMed Res. Intl 2020, e7298687 (2020).
- 8. . Naturally occurring exosome vesicles as potential delivery vehicle for bioactive compounds. Front. Sustain. Food Syst. 3, 23 (2019).
- 9. International Society for Extracellular Vesicles and International Society for Cell and Gene Therapy statement on extracellular vesicles from mesenchymal stromal cells and other cells: considerations for potential therapeutic agents to suppress coronavirus disease-19. Cytotherapy 22(9), 482–485 (2020).
- 10. . Challenges in the development and establishment of exosome-based drug delivery systems. J. Control. Rel. 329, 894–906 (2021).
- 11. . Exosomes in clinical trial and their production in compliance with good manufacturing practice. Tzu Chi Med. J. 32(2), 113–120 (2019).
- 12. Techniques used for the isolation and characterization of extracellular vesicles: results of a worldwide survey. J. Extracell. Vesicles 5, 32945 (2016).
- 13. Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes. Methods 56(2), 293–304 (2012).
- 14. The impact of disparate isolation methods for extracellular vesicles on downstream RNA profiling. J. Extracell. Vesicles 3(1), 24858 (2014).
- 15. . Sustained delivery system for stem cell-derived exosomes. Front Pharmacol. 10, 1368 (2019).
- 16. . Impact of cell culture parameters on production and vascularization bioactivity of mesenchymal stem cell‐derived extracellular vesicles. Bioeng. Transl. Med. 2(2), 170–179 (2017).
- 17. . Prospects and challenges of extracellular vesicle-based drug delivery system: considering cell source. Drug Deliv. 27(1), 585–598 (2020).
- 18. . Unlocking the power of exosomes for crossing biological barriers in drug delivery. Pharmaceutics 13(1), 122 (2021).
- 19. . Transfer of extracellular vesicles during immune cell-cell interactions. Immunol. Rev. 251(1), 125–142 (2013).
- 20. . T cell antigenicity and immunogenicity of allogeneic exosomes. Am. J. Transpl. 21(7), 2583–2589 (2021).
- 21. . Active loading into extracellular vesicles significantly improves the cellular uptake and photodynamic effect of porphyrins. J. Control. Rel. 205, 35–44 (2015).
- 22. Generation and testing of clinical-grade exosomes for pancreatic cancer. JCI Insight 3(8), 99263 (2018).
- 23. . Preservation and storage stability of extracellular vesicles for therapeutic applications. AAPS J. 20(1), 1 (2017).
- 24. . Applications, challenges and prospects of mesenchymal stem cell exosomes in regenerative medicine. Stem Cell Res. Ther. 12(1), 521 (2021).
- 25. . To protect and to preserve: novel preservation strategies for extracellular vesicles. Front Pharmacol. 9, 1199 (2018).
- 26. Engineered exosomes: desirable target-tracking characteristics for cerebrovascular and neurodegenerative disease therapies. Theranostics 11(18), 8926–8944 (2021).
- 27. . Engineering exosomes as refined biological nanoplatforms for drug delivery. Acta Pharmacol. Sin. 38(6), 754–763 (2017).