Exosomes as a novel nanomedicine platform for personalized triple-negative breast cancer therapy
Papers of special note have been highlighted as: • of interest; •• of considerable interest
References
- 1. Exosomes are endogenous nanoparticles that can deliver biological information between cells. Adv. Drug Deliv. Rev. 65(3), 342–347 (2013).
- 2. . Exosomes in triple negative breast cancer: from bench to bedside. Cancer Lett. 527, 1–9 (2022). • Describes the roles of exosomes in triple-negative breast cancer.
- 3. . Theranostic nanomedicine of gold nanoclusters: an emerging platform for cancer diagnosis and therapy. Nanomedicine (Lond.) 11(4), 327–330 (2016).
- 4. . Critical review on the different roles of exosomes in TNBC and exosomal-mediated delivery of microRNA/siRNA/lncRNA and drug targeting signalling pathways in triple-negative breast cancer. Molecules 28(4), 1–20 (2023). •• Complies with exosomal-mediated therapeutics delivery to triple-negative breast cancer.
- 5. . Dendritic cell-targeted theranostic nanomedicine: advanced cancer nanotechnology for diagnosis and therapy. Nanomedicine (Lond.) 15(10), 947–949 (2020).
- 6. . Assessing value of innovative molecular diagnostic tests in the concept of predictive, preventive, and personalized medicine. EPMA J. 6, 1–12 (2015).
- 7. . Advanced optical imaging-guided nanotheranostics towards personalized cancer drug delivery. Nanomaterials (Basel) 12(3), 1–17 (2022).
- 8. . The application of exosomes in the treatment of triple-negative breast cancer. Front. Mol. Biosci. 9, 1022725 (2022).
- 9. . Exosome-based candidates move into the clinic. Nat. Rev. Drug Discov. 20(1), 6–7 (2021).
- 10. Functional exosome-mediated co-delivery of doxorubicin and hydrophobically modified microRNA 159 for triple-negative breast cancer therapy. J. Nanobiotechnol. 17(1), 93 (2019).
- 11. Targeted exosome-encapsulated erastin-induced ferroptosis in triple-negative breast cancer cells. Cancer Sci. 110(10), 3173–3182 (2019). •• Presents iron-assisted apoptosis promoted in triple-negative breast cancer via exosomal delivery of erastin.
- 12. . Modification of extracellular vesicles by fusion with liposomes for the design of personalized biogenic drug delivery systems. ACS Nano 12(7), 6830–6842 (2018).
- 13. Characterization of biomolecular nanoconjugates by high-throughput delivery and spectroscopic difference. Nanomedicine (Lond.) 7(12), 1851–1862 (2012).
- 14. . High-throughput synthesis and screening of rapidly degrading polyanhydride nanoparticles. ACS Comb. Sci. 22(4), 172–183 (2020).
- 15. Integrating artificial intelligence and nanotechnology for precision cancer medicine. Adv. Mater. 32(13), e1901989 (2020).
- 16. Barcoded nanoparticles for high throughput in vivo discovery of targeted therapeutics. Proc. Natl Acad. Sci. USA 114(8), 2060–2065 (2017).
- 17. Predicting clinical response to anticancer drugs using an ex vivo platform that captures tumour heterogeneity. Nat. Commun. 6, 6169 (2015).
- 18. Integrated omics-based pathway analyses uncover CYP epoxygenase-associated networks as theranostic targets for metastatic triple-negative breast cancer. J. Exp. Clin. Cancer Res. 38(1), 187 (2019).
- 19. . Omics-based nanomedicine: the future of personalized oncology. Cancer Lett. 352(1), 126–136 (2014).
- 20. . Safety considerations of cancer nanomedicine–a key step toward translation. Small 16(36), e2000673 (2020). • Demonstrates the safety margin of nanomedicines for clinical translation.