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An update on long-acting agents in HIV therapy

    Laura Pezzati

    Department of Biomedical & Clinical Sciences (DIBIC), Università degli Studi di Milano, Milan, Italy

    Infectious Diseases Unit, ASST Ovest Milanese, Ospedale Nuovo di Legnano, Legnano, Italy

    ,
    Giada Canavesi

    Department of Biomedical & Clinical Sciences (DIBIC), Università degli Studi di Milano, Milan, Italy

    Infectious Diseases Unit, ASST Ovest Milanese, Ospedale Nuovo di Legnano, Legnano, Italy

    &
    Stefano Rusconi

    *Author for correspondence: Tel.: +39 0331 449 680;

    E-mail Address: stefano.rusconi@unimi.it

    Department of Biomedical & Clinical Sciences (DIBIC), Università degli Studi di Milano, Milan, Italy

    Infectious Diseases Unit, ASST Ovest Milanese, Ospedale Nuovo di Legnano, Legnano, Italy

    Published Online:https://doi.org/10.2217/fvl-2023-0097

    Since the advent of highly active antiretroviral therapy, many efforts have been made to broaden the spectrum of possible regimens. Long-acting antiretrovirals, are particularly attractive, since they allow for less frequent dosing and can potentially overcome difficulties associated with daily tablet consumption, including the need for flexibility and privacy. In this article, we present a summary and update on currently available long-acting antiretrovirals and those under development and discuss issues related to their effective implementation.

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