Long noncoding RNA THOR is highly expressed in colorectal cancer and predicts a poor prognosis

Papers of special note have been highlighted as: • of interest; •• of considerable interest

References

• 1. Wolf AMD, Fontham ETH, Church TR et al. Colorectal cancer screening for average-risk adults: 2018 guideline update from the American Cancer Society. CA Cancer J. Clin. 68, 250–281 (2018).
  MedlineGoogle Scholar
• 2. Siegel RL, Miller KD, Jemal SA et al. Cancer Statistics, 2017. CA Cancer J. Clin. 67(1), 7–30 (2017).
  MedlineGoogle Scholar
• 3. Chen W, Zheng R, Zeng H, Zhang S, He J. Annual report on status of cancer in China, 2011. Chin. J. Cancer Res. 27, 2–12 (2015).
  MedlineGoogle Scholar
• 4. Miller KD, Siegel RL, Lin CC et al. Cancer treatment and survivorship statistics, 2016. CA. Cancer J. Clin. 66, 271–289 (2016).
  MedlineGoogle Scholar
• 5. Ransohoff JD, Wei Y, Khavari PA. The functions and unique features of long intergenic non-coding RNA. Nat. Rev. Mol. Cell Biol. 19, 143–157 (2018).
  Medline CASGoogle Scholar
• 6. Strauss M. Hemilaryngectomy rescue surgery for radiation failure in early glottic carcinoma. Laryngoscope 98, 317–320 (1988).
  Medline CASGoogle Scholar
• 7. Di W, Weinan X, Xin L et al. Long noncoding RNA SNHG14 facilitates colorectal cancer metastasis through targeting EZH2-regulated EPHA7. Cell Death Dis. 10(7), 514 (2019).
  MedlineGoogle Scholar
• 8. Ponting CP, Oliver PL, Reik W. Evolution and functions of long noncoding RNAs. Cell 136, 629–641 (2009).
  Medline CASGoogle Scholar
• 9. Qian X, Zhao J, Yeung PY, Zhang QC, Kwok CK. Revealing lncRNA structures and interactions by sequencing-based approaches. Trends Biochem. Sci. 44, 33–52 (2019).
  Medline CASGoogle Scholar
• 10. Hosono Y, Niknafs YS, Prensner JR et al. Oncogenic role of THOR, a conserved cancer/testis long non-coding RNA. Cell 171(7), 1559–1572 (2017). •• The first paper to report the carcinogenic effect of THOR.
  Medline CASGoogle Scholar
• 11. Wang SS, Lv Y, Xu XC et al. Triptonide inhibits human nasopharyngeal carcinoma cell growth via disrupting Lnc-RNA THOR-IGF2BP1 signaling. Cancer Lett. 443, 13–24 (2019). • Provides novel insight into the role of THOR in nasopharyngeal carcinoma.
  Medline CASGoogle Scholar
• 12. Song H, Xu Y, Shi L et al. LncRNA THOR increases the stemness of gastric cancer cells via enhancing SOX9 mRNA stability. Biomed. Pharmacother. 108, 338–346 (2018).
  Medline CASGoogle Scholar
• 13. Shang Y. LncRNA THOR acts as a retinoblastoma promoter through enhancing the combination of c-myc mRNA and IGF2BP1 protein. Biomed. Pharmacother. 106, 1243–1249 (2018).
  Medline CASGoogle Scholar
• 14. Gao L, Cheng XL, Cao H. LncRNA THOR attenuates cisplatin sensitivity of nasopharyngeal carcinoma cells via enhancing cells stemness. Biochimie 152, 63–72 (2018).
  Medline CASGoogle Scholar
• 15. Yang H, Fu G, Liu F et al. LncRNA THOR promotes tongue squamous cell carcinomas by stabilizing IGF2BP1 downstream targets. Biochimie 165, 9–18 (2019).
  Medline CASGoogle Scholar
• 16. Ye XT, Huang H, Huang WP, Hu WL. LncRNA THOR promotes human renal cell carcinoma cell growth. Biochem. Biophys. Res. Commun. 501, 661–667 (2018).
  Medline CASGoogle Scholar
• 17. Chen W, Chen M, Xu Y et al. Long non-coding RNA THOR promotes human osteosarcoma cell growth in vitro and in vivo. Biochem. Biophys. Res. Commun. 499, 913–919 (2018). • Provides novel insight into the role of THOR in human osteosarcoma.
  Medline CASGoogle Scholar
• 18. Cheng Z, Lei Z, Yang P et al. Long non-coding RNA THOR promotes cell proliferation and metastasis in hepatocellular carcinoma. Gene 678, 129–136 (2018).
  Medline CASGoogle Scholar
• 19. Cheng Z, Lei Z, Yang P et al. Long non-coding RNA THOR promotes liver cancer stem cells expansion via β-catenin pathway. Gene 684, 95–103 (2019).
  Medline CASGoogle Scholar
• 20. Wu H, He Y, Chen H et al. LncRNA THOR increases osteosarcoma cell stemness and migration by enhancing SOX9 mRNA stability. FEBS Open Bio. 9, 781–790 (2019).
  Medline CASGoogle Scholar
• 21. Lv Y, Yang X, Wang L. Effect of lncRNA THOR on proliferation and migration of colon cancer cells. Oncol. Lett. 18, 2518–2522 (2019). •• Suggests that THOR may play a role in colon cancer.
  Medline CASGoogle Scholar
• 22. Provenzale D, Gupta S, Ahnen DJ et al. NCCN guidelines insights: colorectal cancer screening, version 1.2018. J. Natl Compr. Canc. Netw. 16, 939–949 (2018).
  MedlineGoogle Scholar
• 23. Edge SB, Compton CC. The American Joint Committee on Cancer: the 7th edition of the AJCC cancer staging manual and the future of TNM. Ann. Surg. Oncol. 17, 1471–1474 (2010).
  MedlineGoogle Scholar
• 24. Jiang MC, Ni JJ, Cui WY, Wang BY, Zhuo W. Emerging roles of lncRNA in cancer and therapeutic opportunities. Am. J. Cancer Res. 9, 1354–1366 (2019).
  Medline CASGoogle Scholar
• 25. Sun W, Ren S, Li R, Zhang Q, Song H. LncRNA, a novel target biomolecule, is involved in the progression of colorectal cancer. Am. J. Cancer Res. 9, 2515–2530 (2019).
  Medline CASGoogle Scholar
• 26. Morin PJ. Colorectal cancer: the APC-lncRNA link. J. Clin. Invest. 129, 503–505 (2019).
  MedlineGoogle Scholar
• 27. Kang W, Zheng Q, Lei J, Chen C, Yu C. Prognostic value of long noncoding RNAs in patients with gastrointestinal cancer: a systematic review and meta-analysis. Dis. Markers 2018, 5340894 (2018).
  MedlineGoogle Scholar