XRCC1 632 as a candidate for cancer predisposition via a complex interaction with genetic variants of base excision repair and double strand break repair genes

Papers of special note have been highlighted as: • of interest; •• of considerable interest

References

• 1. Bishop JM. Molecular themes in oncogenesis. Cell 64(2), 235–248 (1991).
  Medline CASGoogle Scholar
• 2. Levine AJ. The tumor suppressor genes. Ann. Rev. Biochem. 62, 623–651 (1993).
  Medline CASGoogle Scholar
• 3. Sherr CJ. Cancer cell cycles. Science 274, 1672–1677 (1996).
  Medline CASGoogle Scholar
• 4. Hartwell LH, Weinert TA. Checkpoints: controls that assure the order of cell cycle events. Science 246, 629–633 (1989).
  Medline CASGoogle Scholar
• 5. Farber E. The multistep nature of cancer. Cancer Res. 44, 4217–4223 (1984).
  Medline CASGoogle Scholar
• 6. Fearon ER, Vogelstein BA. A genetic model for colorectal tumorigenesis. Cell 61, 759–767 (1990).
  Medline CASGoogle Scholar
• 7. Wei Q, Spitz MR. The role of DNA repair capacity in susceptibility to lung cancer: a review. Cancer Metastasis Rev. 16, 295–307 (1997).
  Medline CASGoogle Scholar
• 8. de Groot P, Munden RF. Lung cancer epidemiology, risk factors, and prevention. Radiol. Clin. North Am. 50(5), 863–876 (2012).
  MedlineGoogle Scholar
• 9. Wiencke JK, Kelesey KT, Varkonyi A et al. Correlation of DNA adducts in blood mononuclear cells with tobacco carcinogen-induced damage in human lung. Cancer Res. 55, 4910–4914 (1995).
  Medline CASGoogle Scholar
• 10. Sancar A, Lindsey-Boltz LA, Unsal-Kacmaz K et al. Molecular mechanism of mammalian DNA repair and the DNA damage checkpoints. Annu. Rev. Biochem. 73, 39–85 (2004).
  Medline CASGoogle Scholar
• 11. Jackson PS, Bartek J. The DNA-damage response in human biology and disease. Nature 461, 1071–1078 (2009).
  Medline CASGoogle Scholar
• 12. Cole BS, Gilbert-Diamond D, Moore JH et al. Analysis of gene–gene interactions. Curr. Protoc. Hum. Genet. 70(1), 1.14.1–1.14.10 (2011).
  Google Scholar
• 13. Kim K, Kwon MS, Oh S et al. Identification of multiple gene–gene interactions for ordinal phenotypes. BMCMed. Genomics. 6(Suppl. 2), 6 (2013).
  Google Scholar
• 14. Singh A, Singh N, Behera D et al. Association and multiple interaction analysis among five XRCC1 polymorphic variants in modulating lung cancer risk in North Indian population. DNA Repair 47, 30–41 (2016).
  Medline CASGoogle Scholar
• 15. Singh A, Singh N, Behera D, Sharma S. Polymorphism in XRCC1 gene modulates survival and clinical outcomes of advanced North Indian lung cancer patients treated with platinum-based doublet chemotherapy. Med. Oncol. 34, 64 (2017).
  MedlineGoogle Scholar
• 16. Singh A, Singh N, Behera D et al. Genetic investigation of polymorphic OGG1 and MUTYH genes towards increased susceptibility in lung adenocarcinoma and its impact on overall survival of lung cancer patients treated with platinum based chemotherapy. Pathol.Oncol.Res. 25 (4), 1327–1340 (2015).
  Google Scholar
• 17. Singh A, Singh N, Behera D et al. Role of polymorphic XRCC6 (K70)/XRCC7 (DNA-PKcs) genes towards susceptibility and prognosis of lung cancer patientsundergoing platinum based doublet chemotherapy. Molecular Biol. Rep. 45 (3), 253–261 (2018).
  Medline CASGoogle Scholar
• 18. Gangwar R, Ahirwar D, Mandhani A et al. Do DNA repair genes OGG1, XRCC3 and XRCC7 have an impact on susceptibility to bladder cancer in the north indian population. Mutation Res. 680(1), 56–63 (2006). • Analyzes major genes involved in the study in Indian population.
  Google Scholar
• 19. Srivastava A, Srivastava K, Pandey SN et al. Single-nucleotide polymorphisms of DNA repair genes OGG1 and XRCC1: association with gallbladder cancer in north Indian population. Ann. Surg. Oncol. 16(6), 1695–1703 (2009).
  MedlineGoogle Scholar
• 20. Szaflik J, Cuchra M, Przybylowska K et al. Association of the 399Arg/Gln XRCC1, the 194 Arg/Trp XRCC1, the 326Ser/Cys OGG1, and the 324 Gln/His Mutyh gene polymorphisms with clinical parameters and the risk for development of primary open angle glaucoma. Mutation. Res. 753(1), 12–22 (2013).
  Medline CASGoogle Scholar
• 21. Letkova L, Matakova T, Musak L et al. DNA repair gene polymorphism and lung cancer risk with the emphasis to sex differences. Mol. Biol. Rep. 40(9), 5261–5273 (2013).
  Medline CASGoogle Scholar
• 22. Przybylowska K, Kabzinski J, Sygut A et al. An association selected polymorphisms of XRCC1, OGG1 and mutyh gene and the level of efficiency oxidative DNA damage repair with a risk of colorectal cancer. Mutation Research 745, 6–15 (2013).
  MedlineGoogle Scholar
• 23. Qian B, Zhang H, Zhang L et al. Association of genetic polymorphisms in DNA repair pathway genes with non-small cell lung cancer risk. Lung Cancer 73(2), 138–146 (2011).
  MedlineGoogle Scholar
• 24. Huang M, Dinney CP, Lin X et al. High order interactions among genetic variants in DNA base excision repair pathway genes and smoking in bladder cancer susceptibility. Cancer Epidemiol. Biomark. Prev. 16(1), 84–91 (2007).
  Medline CASGoogle Scholar
• 25. Zhi Y, Jing Y, Yang L et al. Interaction between polymorphisms of DNA repair genes significantly modulated bladder cancer risk. Int. J. Med. Sci. 9(6), 498 (2012).
  Medline CASGoogle Scholar
• 26. Michiels S, Laplanche A, Boulet T et al. Genetic polymorphisms in 85 DNA repair genes and bladder cancer risk. Carcinogenesis 30(5), 763–768 (2009).
  Medline CASGoogle Scholar
• 27. Patil MN, Datkhile KD, Bhosale SJ et al. Role of genetic polymorphisms in XRCC4, XRCC5, XRCC6 and XRCC7 in breast cancer susceptibility in rural Indian population: a hospital based case–control study from Maharashtra. Int. J. Health Sci. Res. 6(11), 24–32 (2016). •• The study compared genes for the first time taken up in the present study in Indian population.
  Google Scholar
• 28. Datkhile K, Vhaval RD, Patil MN et al. Role of genetic polymorphisms in DNA repair genes (XRCC1, XRCC2, XRCC3, XRCC4, XRCC5, XRCC6, XRCC7) in head and neck cancer susceptibility in rural Indian population: a hospital based case–control study from south-western maharashtra. Int. J. Curr. Res. 8, 25482–25492 (2016).
  CASGoogle Scholar
• 29. Horikawa Y, Gu J, Wu X. Genetic susceptibility to bladder cancer with an emphasis on gene–gene and gene–environmental interactions. Curr. Opin. Urol. 18(5), 493–498 (2008).
  MedlineGoogle Scholar
• 30. Rai R, Kim JJ, Misra S et al. A multiple interaction analysis reveals adrb3 as a potential candidate for gallbladder cancer predisposition via a complex interaction with other candidate gene variations. Int. J. Mol. Sci. 16(12), 28038–28049 (2015).
  Medline CASGoogle Scholar
• 31. Das S, Bhowmik A, Bhattacharjee A et al. XPD, APE1, and MUTYH polymorphisms increase head and neck cancer risk: effect of gene–gene and gene–environment interactions. Tumor Biology 36(10), 7569–7579 (2015).
  Medline CASGoogle Scholar
• 32. Ritchie MD, Hahn HW, Roodi N et al. Multifactor-dimensionality reduction reveals high-order interactions among estrogen–metabolism genes in sporadic breast cancer. Am. J. Human Genetics 69(1), 138–147 (2001).
  Medline CASGoogle Scholar
• 33. Liu L, Wu C, Wang Y et al. Association of candidate genetic variations with gastric cardia adenocarcinoma in Chinese population: a multiple interaction analysis. Carcinogenesis 32(3), 336–342 (2010).
  MedlineGoogle Scholar
• 34. Liu L, Wu J, Zhong R et al. Multi-loci analysis reveals the importance of genetic variations in sensitivity of platinum-based chemotherapy in non-small-cell lung cancer. Mol. Carcinog. 52, 923–931 (2013).
  Medline CASGoogle Scholar
• 35. Huang M, Dinney CP, Lin X et al. High-order interactions among genetic variants in DNA base excision repair pathway genes and smoking in bladder cancer susceptibility. Cancer Epidemiol. Biomark. Prev. 16, 84–91 (2007). • Depicts a high order interactions in base excision repair pathway in relation to smoking.
  Medline CASGoogle Scholar