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Importance of lactate/albumin ratio in pediatric nosocomial infection and mortality at different times

    Hatice Feray Arı

    *Author for correspondence: Tel.: +90 505 685 4923;

    E-mail Address: dr.hferayyavas@gmail.com

    Aydın Gynecology & Pediatrics Hospital, Pediatric Intensive Care Department, Efeler, Aydın, 09020, Turkey

    ,
    Adem Keskin

    Department of Medicine Biochemistry, Institute of Health Sciences, Aydin Adnan Menderes University, Efeler, Aydın, 09100, Turkey

    ,
    Murat Arı

    Soke Vocational School of Health Services, Aydın Adnan Menderes University, Soke, Aydın, 09200, Turkey

    &
    Recai Aci

    Department of Biochemistry, Samsun Training & Research Hospital, Ilkadim, Samsun, 55090, Turkey

    Published Online:https://doi.org/10.2217/fmb-2023-0125

    Aim: To evaluate the lactate/albumin ratio and its relation to mortality in children with nosocomial infections. Materials & methods: One hundred six children were included in this study. Blood gas and albumin levels were analyzed at the first, 24th and 48th h. Results: The types of detected microbial agents, signs of sepsis, development of septic shock and mortality rates were different. The first-, 24th- and 48th h lactate levels of the children who died were higher than those of the living children, but the albumin levels were lower. The highest area under the curve value for the lactate/albumin ratio was detected at the 24th h. Conclusion: Lactate/albumin ratio can be used to predict mortality in children with nosocomial infections.

    Tweetable abstract

    The lactate/albumin ratio is a useful indicator for predicting mortality in children with nosocomial infections. This study finds that comparing values at 24 h may provide the best indicator of outcome.

    Papers of special note have been highlighted as: • of interest; •• of considerable interest

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