Special Report

Department of Physiology, School of Basic Medical Sciences, Hubei University of Science & Technology, Xianning, 437100, China

*Author for correspondence:

E-mail Address: dinglq2021@163.com

https://orcid.org/0000-0003-0508-7531

Department of Pharmaceutics, School of Pharmacy, Hubei University of Science & Technology, Xianning, 437100, China

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Published Online:16 Aug 2023https://doi.org/10.2217/fmb-2023-0090

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Abstract

HSV can evade host defenses and cause lifelong infection and severe illness. Lysosomes are catabolic organelles that play an important role in the regulation of cellular homeostasis. Lysosomal dysfunction and alterations in the process of autophagy have been identified in a variety of diseases, including HSV infection, and targeting lysosomes is a potential anti-HSV therapeutic strategy. This article reviews the role of lysosomes and lysosome-associated proteins in HSV infection, providing attractive targets and novel strategies for the treatment of HSV infection.

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Lysosomes play an important role in the regulation of cellular homeostasis, and targeting lysosomes is a potential anti-HSV therapeutic strategy. This article takes a look at the role of lysosomes and lysosome-associated proteins in HSV infection.

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Papers of special note have been highlighted as: • of interest

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Vol. 18, No. 13

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History

Received 22 April 2023

Accepted 19 June 2023

Published online 16 August 2023

Published in print September 2023

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Keywords

Author contributions

J Ding wrote the manuscript. L Ding conceived the work and revised the manuscript. Both authors read and approved the final manuscript.

Financial & competing interests disclosure

This work was supported by the Initial Scientific Research Fund of PhD in Hubei University of Science and Technology (BK202120). The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.

No writing assistance was utilized in the production of this manuscript.

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Role of lysosomes in HSV-induced pathogenesis

Abstract

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References