Tree-inhabiting polypore fungi as sources of a cornucopia of bioactive compounds

References

• 1. Gilhen-Baker M, Roviello V, Beresford-Kroeger D, Roviello GN. Old growth forests and large old trees as critical organisms connecting ecosystems and human health. A review. Environ. Chem. Lett. 20(2), 1529–1538 (2022).
  Medline CASGoogle Scholar
• 2. Grunewald F, Steinborn C, Huber R et al. Effects of Birch Polypore Mushroom, Piptoporus betulinus (Agaricomycetes), the “Iceman's Fungus”, on human immune cells. Int. J. Med. Mushrooms 20(12), 1135–1147 (2018).
  MedlineGoogle Scholar
• 3. Girometta C. Antimicrobial properties of Fomitopsis officinalis in the light of its bioactive metabolites: a review. Mycology 10(1), 32–39 (2018).
  MedlineGoogle Scholar
• 4. Piętka J, Grzywacz A. In situ inoculation of larch with the threatened wood-decay fungus Fomitopsis officinalis (Basidiomycota) – experimental studies. Pol. Bot. J. 50(2), 225–231 (2005).
  Google Scholar
• 5. Slomski A. Trials test mushrooms and herbs as anti-COVID-19 agents. JAMA 326(20), 1997 (2021).
  Medline CASGoogle Scholar
• 6. Roviello V, Roviello GN. Lower COVID-19 mortality in Italian forested areas suggests immunoprotection by Mediterranean plants. Environ. Chem. Lett. 19(1), 699–710 (2020).
  MedlineGoogle Scholar
• 7. Unlu A, Nayir E, Kirca O, Ozdogan M. Ganoderma lucidum (reishi mushroom) and cancer. J. BUON 21(4), 792–798 (2016).
  MedlineGoogle Scholar
• 8. Jin H, Jin F, Jin J-X et al. Protective effects of Ganoderma lucidum spore on cadmium hepatotoxicity in mice. Food Chem. Toxicol. 52, 171–175 (2013).
  Medline CASGoogle Scholar
• 9. Stamets PE. Medicinal polypores of the forests of North America: screening for novel antiviral activity. Int. J. Med. Mushrooms 7(3), 362 (2005).
  Google Scholar
• 10. Grienke U, Zöll M, Peintner U, Rollinger JM. European medicinal polypores – a modern view on traditional uses. J. Ethnopharmacol. 154(3), 564–583 (2014).
  MedlineGoogle Scholar
• 11. Muszyńska B, Fijałkowska A, Sułkowska‐Ziaja K et al. Fomitopsis officinalis: a species of arboreal mushroom with promising biological and medicinal properties. Chem. Biodivers. 17(6), e2000213 (2020).
  Medline CASGoogle Scholar
• 12. Rai MK, Gaikwad S, Nagaonkar D, dos Santos CA. Current advances in the antimicrobial potential of species of genus Ganoderma (higher Basidiomycetes) against human pathogenic microorganisms (review). Int. J. Med. Mushrooms 17(10), 921–932 (2015).
  MedlineGoogle Scholar
• 13. Grienke U, Kaserer T, Pfluger F et al. Accessing biological actions of Ganoderma secondary metabolites by in silico profiling. Phytochemistry 114, 114–124 (2015).
  Medline CASGoogle Scholar
• 14. Zjawiony JK. Biologically active compounds from Aphyllophorales (Polypore) fungi. J. Nat. Prod. 67(2), 300–310 (2004).
  Medline CASGoogle Scholar
• 15. Tochikura TS, Nakashima H, Ohashi Y, Yamamoto N. Inhibition (in vitro) of replication and of the cytopathic effect of human immunodeficiency virus by an extract of the culture medium of Lentinus edodes mycelia. Med. Microbiol. Immunol. 177(5), 235–244 (1988).
  Medline CASGoogle Scholar
• 16. Ikekawa T, Uehara N, Maeda Y, Nakanishi M, Fukuoka F. Antitumor activity of aqueous extracts of edible mushrooms. Cancer Res. 29(3), 734–735 (1969).
  Medline CASGoogle Scholar
• 17. Mizuno T. Bioactive biomolecules of mushrooms: food function and medicinal effect of mushroom fungi. Food Rev. Int. 11(1), 5–21 (1995).
  Google Scholar
• 18. Tsukagoshi S. Krestin (PSK). Cancer Treat. Rev. 11(2), 131–155 (1984).
  Medline CASGoogle Scholar
• 19. Lu H, Yang Y, Gad E et al. Polysaccharide krestin is a novel TLR2 agonist that mediates inhibition of tumor growth via stimulation of CD8 T cells and NK cells. Clin. Cancer Res. 17(1), 67–76 (2011).
  Medline CASGoogle Scholar
• 20. Bleha R, Třešnáková L, Sushytskyi L et al. Polysaccharides from basidiocarps of the polypore fungus Ganoderma resinaceum: isolation and structure. Polymers 14(2), 255 (2022).
  Medline CASGoogle Scholar
• 21. Gow NAR, Latge J-P, Munro CA, Heitman J. The fungal cell wall: structure, biosynthesis, and function. Microbiol. Spectr. 5(3), 5–3 (2017).
  Google Scholar