Research Article

Infectious Diseases Research Center, Golestan University of Medical Sciences, Gorgan, 4934174515, Iran

PhD candidate in Microbiology, Department of Microbiology & Microbial Biotechnology, Faculty of Life Sciences & Biotechnology, Shahid Beheshti University, Tehran, Iran

Seyed Amir Soltani

Master of Health Services Management, Golestan University of Medical Sciences, Gorgan, 4934174515, Iran

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Akram Taheri Rad

Master of Microbiology, Department of Microbiology, Golestan University of Medical Sciences, Gorgan, 4934174515, Iran

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Zahra Mehrbakhsh

PhD candidate in Biostatics, Department of Biostatistics, School of Health, Hamedan University of Medical sciences, Hamadan, Iran

PhD candidate, Department of Biostatistics, School of Health, Golestan University of Medical sciences, Gorgan, 4934174515, Iran

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Sina Sodagar

Basic Sciences, Laboratory Sciences Research Center, Golestan University of Medical Sciences, Gorgan, 4934174515, Iran

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Alireza Tahamtan

Infectious Diseases Research Center, Golestan University of Medical Sciences, Gorgan, 4934174515, Iran

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Seyedeh Sedigheh Hosseini

*Author for correspondence: Tel.: +989 113 757 1228;

E-mail Address: Hosseini.s@goums.ac.ir

https://orcid.org/0000-0002-6250-6416

Basic Sciences, Laboratory Sciences Research Center, Golestan University of Medical Sciences, Gorgan, 4934174515, Iran

Asistant professor, Department of Labratory Sciences, Faculty of Paramedicine, Golestan University of Medical Sciences, Gorgan, 4934174515, Iran

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Published Online:25 Apr 2022https://doi.org/10.2217/fmb-2022-0041

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Abstract

Background: The aim of this study was to evaluate reinfection and fungal infections among 785 patients with COVID-19 disease admitted to Baqiyatallah Hospital in Northeastern Iran after the onset of the COVID-19 epidemic. Materials & Methods: In this descriptive-analytic study (20 February–21 July 2020), reinfection and fungal infections among 785 patients were investigated using epidemiological questionnaire, clinical trials, Real-time PCR and CT scan (chest computed tomography) from the hospital HIS (hospital's information system) and collected samples. Results: Reinfection and one oral candidiasis were diagnosed in one 68-year-old man and one 47-year-old man 63 and 42 days after the initial infection, respectively. Conclusion: The research results showed that exposure to COVID-19 may not establish long-term protective immunity to all patients.

Keywords:

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Vol. 17, No. 9

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History

Received 15 February 2022

Accepted 22 March 2022

Published online 25 April 2022

Published in print June 2022

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Keywords

Author contributions

SS Hosseini conceptualized and designed the study. M Naderi, AT Rad, SA Soltani and S Sodagar collected data. Z Mehrbakhsh analyzed the collected data. M Naderi, SS Hosseini and A Tahamtan drafted the manuscript. All authors evaluated and edited the manuscript. All authors have read and approved the final manuscript.

Acknowledgments

The authors would like to thank Golestan University of Medical Sciences and the laboratory and the nursing team of Baqiyatallah Hospital that are fighting against the illness.

Financial & competing interests disclosure

The authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.

No writing assistance was utilized in the production of this manuscript.

Ethical conduct of research

The current study was extracted from a research protocol approved by (11588) University of Medical Sciences, Gorgan, Iran of Ethics Committee (approval code: IR. GUMS. rec. 1399.035). The volunteer who had oral candidiasis gave written consent. The rest of the files were read from the HIS system of the hospital and the patients' files were obtained with the permission of the Ethics Committee of (approval code: IR. GUMS. rec. 1399.035) University of Medical Sciences with the code (11588). This article does not contain any studies with animals performed by any of the authors.

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Recurrent viral RNA positivity and candidiasis findings in hospitalized patients with COVID-19

Abstract

References