Abstract
The SET gene has four transcripts reported in NCBI, coding two isoforms of SET proteins. The most known function of SET protein is inhibiting protein phosphatase 2A, a tumor suppressor, which has been associated with different biological processes. In this review, our focus was on exploring the other SET functions related to epigenetic mechanisms, which impact cellular migration, cell cycle and apoptosis.
Tweetable abstract
SET protein is responsible for regulating essential epigenetic processes. The disrupted function of SET in cancer makes it a promising target for research.
Papers of special note have been highlighted as: • of interest; •• of considerable interest
References
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