Systemic immune-inflammation index is a novel marker to predict functionally significant coronary artery stenosis

Papers of special note have been highlighted as: • of interest; •• of considerable interest

References

• 1. Knuuti J, Wijns W, Saraste A et al. 2019 ESC Guidelines for the diagnosis and management of chronic coronary syndromes: the task force for the diagnosis and management of chronic coronary syndromes of the European Society of Cardiology (ESC). Eur. Heart J. 41(3), 407–477 (2020). •• Reports the most recent recommendations of European Society of Cardiology for the diagnosis and management of patients with chronic coronary syndrome.
  MedlineGoogle Scholar
• 2. Chowdhury M, Osborn EA. Physiological assessment of coronary lesions in 2020. Curr. Treat. Options Cardiovasc. Med. 22(1), 1–17 (2020).
  MedlineGoogle Scholar
• 3. De Luca G, Venegoni L, Iorio S, Giuliani L, Marino P. Effects of increasing doses of intracoronary adenosine on the assessment of fractional flow reserve. JACC Cardiovasc. Interv. 4(10), 1079–1084 (2011).
  MedlineGoogle Scholar
• 4. Pant S, Deshmukh A, Gurumurthy GS et al. Inflammation and atherosclerosis – revisited. J. Cardiovasc. Pharmacol. Ther. 19(2), 170–178 (2014). • Reports the role of inflammation in atherosclerosis and coronary heart disease.
  Medline CASGoogle Scholar
• 5. Afari ME, Bhat T. Neutrophil to lymphocyte ratio (NLR) and cardiovascular diseases: an update. Expert Rev. Cardiovasc. Ther. 14(5), 573–577 (2016).
  Medline CASGoogle Scholar
• 6. Balta S, Ozturk C. The platelet-lymphocyte ratio: a simple, inexpensive and rapid prognostic marker for cardiovascular events. Platelets 26(7), 680–681 (2015).
  Medline CASGoogle Scholar
• 7. Sari I, Sunbul M, Mammadov C et al. Relation of neutrophil-to-lymphocyte and platelet-to-lymphocyte ratio with coronary artery disease severity in patients undergoing coronary angiography. Kardiol. Pol. 73(12), 1310–1316 (2015).
  MedlineGoogle Scholar
• 8. Kurtul S, Sarli B, Baktir AO et al. Neutrophil to lymphocyte ratio predicts SYNTAX score in patients with non-ST segment elevation myocardial infarction. Int. Heart J. 56(1), 18–21 (2015).
  MedlineGoogle Scholar
• 9. Yilmaz S, Canpolat U, Baser K, Unal S, Kuyumcu MS, Aydogdu S. Neutrophil-to-lymphocyte ratio predicts functionally significant coronary artery stenosis in patients with stable coronary artery disease. Turk. Kardiyol. Dern. Ars. 46(2), 129–135 (2018).
  MedlineGoogle Scholar
• 10. Akyel A, Yayla C, Erat M et al. Neutrophil-to-lymphocyte ratio predicts hemodynamic significance of coronary artery stenosis. Anatol. J. Cardiol. 15(12), 1002–1007 (2015). • Reports the role of neutrophil-to-lymphocyte ratio for predicting hemodynamically significant coronary artery stenosis.
  MedlineGoogle Scholar
• 11. Hu B, Yang XR, Xu Y et al. Systemic immune-inflammation index predicts prognosis of patients after curative resection for hepatocellular carcinoma. Clin. Cancer Res. 20(23), 6212–6222 (2014).
  Medline CASGoogle Scholar
• 12. Hong X, Cui B, Wang M, Yang Z, Wang L, Xu Q. Systemic immune-inflammation index, based on platelet counts and neutrophil-lymphocyte ratio, is useful for predicting prognosis in small cell lung cancer. Tohoku J. Exp. Med. 236(4), 297–304 (2015).
  Medline CASGoogle Scholar
• 13. Huang L, Liu S, Lei Y et al. Systemic immune-inflammation index, thymidine phosphorylase and survival of localized gastric cancer patients after curative resection. Oncotarget 7(28), 44185–44193 (2016).
  MedlineGoogle Scholar
• 14. Huang J, Zhang Q, Wang R et al. Systemic immune-inflammatory index predicts clinical outcomes for elderly patients with acute myocardial infarction receiving percutaneous coronary intervention. Med. Sci. Monit. 25, 9690–9701 (2019). • Reports the prognostic role of systemic immune-inflammation index (SII) in acute myocardial infarction patients.
  MedlineGoogle Scholar
• 15. Levey AS, Coresh J, Balk E et al. National Kidney Foundation practice guidelines for chronic kidney disease: evaluation, classification, and stratification. Ann. Intern. Med. 139(2), 137–147 (2003).
  MedlineGoogle Scholar
• 16. Shaw LJ, Heller GV, Casperson P et al. Gated myocardial perfusion single photon emission computed tomography in the clinical outcomes utilizing revascularization and aggressive drug evaluation (COURAGE) trial, Veterans Administration Cooperative study no. 424. J. Nucl. Cardiol. 13(5), 685–698 (2006).
  MedlineGoogle Scholar
• 17. Pijls NH, van Schaardenburgh P, Manoharan G et al. Percutaneous coronary intervention of functionally nonsignificant stenosis: 5-year follow-up of the DEFER study. J. Am. Coll. Cardiol. 49(21), 2105–2111 (2007).
  MedlineGoogle Scholar
• 18. Xaplanteris P, Fournier S, Pijls NHJ et al. Five-year outcomes with PCI guided by fractional flow reserve. N. Engl. J. Med. 379(3), 250–259 (2018).
  MedlineGoogle Scholar
• 19. Zhang D, Lv S, Song X et al. Fractional flow reserve versus angiography for guiding percutaneous coronary intervention: a meta-analysis. Heart 101(6), 455–462 (2015). •• Reports the beneficial role of fractional flow reserve guided percutaneous coronary intervention strategy in coronary artery disease patients.
  MedlineGoogle Scholar
• 20. Balta S, Celik T, Mikhailidis DP et al. The relation between atherosclerosis and the neutrophil-lymphocyte ratio. Clin. Appl. Thromb. Hemost. 22(5), 405–411 (2016).
  Medline CASGoogle Scholar
• 21. Ommen SR, Gibbons RJ, Hodge DO, Thomson SP. Usefulness of the lymphocyte concentration as a prognostic marker in coronary artery disease. Am. J. Cardiol. 79(6), 812–814 (1997).
  Medline CASGoogle Scholar
• 22. Nunez J, Minana G, Bodi V et al. Low lymphocyte count and cardiovascular diseases. Curr. Med. Chem. 18(21), 3226–3233 (2011).
  Medline CASGoogle Scholar
• 23. Gawaz M, Langer H, May AE. Platelets in inflammation and atherogenesis. J. Clin. Invest. 115(12), 3378–3384 (2005). •• Reports the pathogenetic role of platelets in atherothrombosis.
  Medline CASGoogle Scholar
• 24. Geng Y, Shao Y, Zhu D et al. Systemic immune-inflammation index predicts prognosis of patients with esophageal squamous cell carcinoma: a propensity score-matched analysis. Sci. Rep. 6, 39482 (2016). • Reports the prognostic role of SII in patients with esophageal squamous cell carcinoma. The prognostic value of SII is superior to other conventional biomarkers such as neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio.
  Medline CASGoogle Scholar
• 25. Gao Y, Guo W, Cai S et al. Systemic immune-inflammation index (SII) is useful to predict survival outcomes in patients with surgically resected esophageal squamous cell carcinoma. J. Cancer 10(14), 3188–3196 (2019).
  Medline CASGoogle Scholar