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The role of presepsin in the diagnosis of chronic obstructive pulmonary disease acute exacerbation with pneumonia

    Ali Halıcı

    Department of Emergency Medicine, University of Health Sciences, Diskapi Yildirim Beyazit Training & Research Hospital, 06145, Ankara, Turkey

    ,
    İzzettin Hür

    Department of Emergency Medicine, University of Health Sciences, Diskapi Yildirim Beyazit Training & Research Hospital, 06145, Ankara, Turkey

    ,
    Kerim Abatay

    Department of Emergency Medicine, University of Health Sciences, Diskapi Yildirim Beyazit Training & Research Hospital, 06145, Ankara, Turkey

    ,
    Esra Çetin

    Department of Biochemistry, University of Health Sciences, Diskapi Yildirim Beyazit Training & Research Hospital, 06145, Ankara, Turkey

    ,
    Filiz Halıcı

    Department of Family Medicine, University of Health Sciences, Diskapi Yildirim Beyazit Training & Research Hospital, 06145, Ankara, Turkey

    &
    Seda Özkan

    *Author for correspondence: Tel.: +90 212 414 3434;

    E-mail Address: sedacil@gmail.com

    Department of Emergency Medicine, University of Istanbul-Cerrahpasa, Faculty of Medical, 34098, Istanbul, Turkey

    Published Online:https://doi.org/10.2217/bmm-2019-0183

    Aim: In this study, we aimed to investigate the role of presepsin in detecting concomitant pneumonia in patients presenting with acute exacerbation of chronic obstructive pulmonary disease (COPD) in the emergency department. Patients & methods: Three groups were formed in the study. Group 1: patients diagnosed with acute exacerbation of COPD; group 2: patients with acute exacerbation of COPD + pneumonia; group 3: healthy individuals. Results: Presepsin levels of the patients in group 2 were significantly higher than those of group 1 and group 3 (p < 0.05). There was a statistically significant difference in erythrocyte sedimentation rate, CRP, procalcitonin and presepsin values between two patient groups (p < 0.05). Conclusion: Presepsin can be used to diagnose pneumonia in patients with acute exacerbation of COPD admitted to the emergency department.

    Papers of special note have been highlighted as: • of interest; •• of considerable interest

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