Research Article

Comparison of monocyte with high density lipoprotein cholesterol ratio in dipper and nondipper hypertensive patients

Murat Selcuk

Ersin Yildirim

Faysal Saylik

Murat Selcuk

Department of Cardiology, Van Education & Research Hospital, University of Health Sciences, Van, Turkey

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Ersin Yildirim

*Author for correspondence: Tel.: +90 5370 466 515; +90 5059 231 696; Fax: +90 216 3379 719;

E-mail Address: ersinyild44@gmail.com

https://orcid.org/0000-0002-3311-1095

Department of Cardiology, Umraniye Education & Research Hospital, University of Health Sciences, Istanbul, Turkey

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Faysal Saylik

Department of Cardiology, Van Education & Research Hospital, University of Health Sciences, Van, Turkey

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Published Online:9 Oct 2019https://doi.org/10.2217/bmm-2019-0062

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Abstract

Aim: We aimed to compare the monocyte to HDL-cholesterol ratio (MHR) of nondipper hypertension (NDHT) and dipper hypertension patients. Patients & methods: A total of 162 patients were included in the study. Patients were grouped as dipper and nondipper according to 24-h ambulatory blood pressure recordings. Results: The MHR was significantly higher in nondipper hypertension group compared with control (p < 0.001) and dipper hypertension groups (p = 0.03). MHR, hs-CRP and red-cell distribution width (RDW) were independent predictors of nondipper hypertension. Area under the curve was 0.62 (p = 0.034) for MHR and 0.61 (p = 0.012) for hs-CRP in the ROC analysis. Conclusion: MHR has elevated levels in NDHT patients. Increased levels of MHR may evaluate as increased risk of cardiovascular events in NDHT patients.

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Papers of special note have been highlighted as: • of interest; •• of considerable interest

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Vol. 13, No. 15

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History

Received 8 February 2019

Accepted 22 July 2019

Published online 9 October 2019

Published in print October 2019

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Financial & competing interests disclosure

The authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.

No writing assistance was utilized in the production of this manuscript.

Ethical conduct of research

The study protocol was approved by the Van Education and Research Hospital Ethical Committee. The study was performed in accordance to the Declaration of Helsinki and with the informed consent of all participants.

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