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Opioid trials: time for a new approach? Enriched enrollment randomized gradual withdrawal designs

    Stephen E Nadeau

    *Author for correspondence: Tel.: +1 352 548 6551;

    E-mail Address: snadeau@ufl.edu

    Research Service & the Brain Rehabilitation Research Center, Malcom Randall VA Medical Center & the Department of Neurology, University of Florida College of Medicine, Gainesville, FL 32608-1197, USA

    ,
    Natalie J DelRocco

    Department of Biostatistics, University of Florida College of Public Health & Health Professions & College of Medicine, Gainesville, FL 32611-7450, USA

    &
    Samuel S Wu

    Department of Biostatistics, University of Florida College of Public Health & Health Professions & College of Medicine, Gainesville, FL 32611-7450, USA

    Published Online:https://doi.org/10.2217/pmt-2021-0112
    Free first page

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