Review of recent research on biomedical applications of electrospun polymer nanofibers for improved wound healing

References

• 1 Abrigo M, McArthur SL, Kingshott P. Electrospun nanofibers as dressings for chronic wound care: advances, challenges, and future prospects. Macromol. Biosci. 14(6), 772–792 (2014).Crossref, Medline, CAS, Google Scholar
• 2 Mogoşanu GD, Grumezescu AM. Natural and synthetic polymers for wounds and burns dressing. Int. J. Pharm. 463(2), 127–136 (2014).Crossref, Medline, CAS, Google Scholar
• 3 Fan L, Wang H, Zhang K et al. Vitamin C-reinforcing silk fibroin nanofibrous matrices for skin care application. RSC Adv. 2(10), 4110 (2012).Crossref, CAS, Google Scholar
• 4 Zahedi P, Rezaeian I, Ranaei-Siadat SO, Jafari SH, Supaphol P. A review on wound dressings with an emphasis on electrospun nanofibrous polymeric bandages. Polym. Adv. Technol. 21(2), 77–95 (2010).Crossref, CAS, Google Scholar
• 5 Choi JS, Choi SH, Yoo HS. Coaxial electrospun nanofibers for treatment of diabetic ulcers with binary release of multiple growth factors. J. Mater. Chem. 21(14), 5258 (2011).Crossref, CAS, Google Scholar
• 6 Kumbar SG, James R, Nukavarapu SP, Laurencin CT. Electrospun nanofiber scaffolds: engineering soft tissues. Biomed. Mater. 3(3), 034002 (2008).Crossref, Medline, CAS, Google Scholar
• 7 Zhong SP, Zhang YZ, Lim CT. Tissue scaffolds for skin wound healing and dermal reconstruction. Wiley Interdiscip. Rev. Nanomed. Nanobiotechnol. 2(5), 510–525 (2010).Crossref, Medline, CAS, Google Scholar
• 8 Mansbridge J. Skin tissue engineering. J. Biomater. Sci. Polym. Ed. 19(8), 1–9 (2008).Crossref, Medline, Google Scholar
• 9 Gaffal E, Cron M, Glodde N et al. Cannabis 1 receptors in keratinocytes modulate proinflammatory chemokine secretion and attenuate contact allergic inflammation. J. Immunol. 190, 4929–4936 (2013).Crossref, Medline, CAS, Google Scholar
• 10 Brisbois EJ, Handa H, Meyerhoff ME. Advanced Polymers in Medicine. Springer, Switzerland (2015).Google Scholar
• 11 Iozzo RV. Basement membrane proteoglycans: from cellar to ceiling. Nat. Rev. Mol. Cell Biol. 6(8), 646–656 (2005).Crossref, Medline, CAS, Google Scholar
• 12 Ashcroft GS, Greenwell-Wild T, Horan MA, Wahl SM, Ferguson MW. Topical estrogen accelerates cutaneous wound healing in aged humans associated with an altered inflammatory response. Am. J. Pathol. 155(4), 1137–1146 (1999).Crossref, Medline, CAS, Google Scholar
• 13 Thornton MJ. The biological actions of estrogens on skin. Exp. Dermatol. 11(6), 487–502 (2002).Crossref, Medline, CAS, Google Scholar
• 14 Lazarus GS, Cooper DM, Knighton DR et al. Definitions and guidelines for assessment of wounds and evaluation of healing. Arch. Dermatol. 130(4), 489–493 (1994).Crossref, Medline, CAS, Google Scholar
• 15 Hendrickson D, Virgin J. Factors that affect equine wound repair. Vet. Clin. North Am. Equine Pract. 21(1), 33–44 (2005).Crossref, Medline, Google Scholar
• 16 Ferreira MC, Tuma P, Carvalho VF, Kamamoto F. Complex wounds. Clinics (Sao Paulo) 61(6), 571–578 (2006).Crossref, Medline, Google Scholar
• 17 Moore K, McCallion R, Searle RJ, Stacey MC, Harding KG. Prediction and monitoring the therapeutic response of chronic dermal wounds. Int. Wound J. 3(2), 89–96 (2006).Crossref, Medline, Google Scholar
• 18 Bhattarai N, Edmondson D, Veiseh O, Matsen FA, Zhang M. Electrospun chitosan-based nanofibers and their cellular compatibility. Biomaterials 26(31), 6176–6184 (2005).Crossref, Medline, CAS, Google Scholar
• 19 Strodtbeck F. Physiology of wound healing. Newborn Infant Nurs. Rev. 1(1), 43–52 (2001).Crossref, Google Scholar
• 20 Shakespeare P. Burn wound healing and skin substitutes. Burns 27, 517–522 (2001).Crossref, Medline, CAS, Google Scholar
• 21 Boateng JS, Matthews KH, Stevens HNE, Eccleston GM. Wound healing dressings and drug delivery systems: a review. J. Pharm. Sci. 97(8), 2892–2923 (2008).Crossref, Medline, CAS, Google Scholar
• 22 Rieger KA, Birch NP, Schiffman JD. Designing electrospun nanofiber mats to promote wound healing – a review. J. Mater. Chem. B 1, 4531 (2013).Crossref, Medline, CAS, Google Scholar
• 23 Baum CL, Arpey CJ. Normal cutaneous wound healing: clinical correlation with cellular and molecular events. Dermatol. Surg. 31(6), 674–686 (2005).Crossref, Medline, CAS, Google Scholar
• 24 Shai A, Maibach HI. Wound healing and ulcers of the skin: diagnosis and therapy - the practical approach. Practical Diabetes International 22(8), 283 (2005).Google Scholar
• 25 Wilgus TA. Immune cells in the healing skin wound: influential players at each stage of repair. Pharmacol. Res. 58(2), 112–116 (2008).Crossref, Medline, CAS, Google Scholar
• 26 Diegelmann RF, Evans MC. Wound healing: an overview of acute, fibrotic and delayed healing. Front. Biosci. 9(4), 283–289 (2004).Crossref, Medline, CAS, Google Scholar
• 27 Jayakumar R, Prabaharan M, Sudheesh Kumar PT, Nair SV, Tamura H. Biomaterials based on chitin and chitosan in wound dressing applications. Biotechnol. Adv. 29(3), 322–337 (2011).Crossref, Medline, CAS, Google Scholar
• 28 Daunton C, Kothari S, Smith L, Steele D. A history of materials and practices for wound management. Wound Practice & Research 20(4), 174 (2012).Google Scholar
• 29 Jones VJ. The use of gauze: will it ever change? Int. Wound J. 3(2), 79–86 (2006).Crossref, Medline, Google Scholar
• 30 Eaglstein WH. Moist wound healing with occlusive dressings: a clinical focus. Dermatologic. Surg. 27, 175–181 (2001).Medline, CAS, Google Scholar
• 31 Winter GD. Formation of the scab and the rate of epithelisation of superficial wounds in the skin of the young domestic pig. Nature 193(4812), 293–294 (1962).Crossref, Medline, CAS, Google Scholar
• 32 Macaya D, Spector M. Injectable hydrogel materials for spinal cord regeneration: a review. Biomed. Mater. 7(1), 012001 (2012).Crossref, Medline, CAS, Google Scholar
• 33 Biazar E, Roveimiab Z, Shahhosseini G, Khataminezhad M, Zafari M, Majdi A. Biocompatibility evaluation of a new hydrogel dressing based on polyvinylpyrrolidone/polyethylene glycol. J. Biomed. Biotechnol. 2012, 343989 (2012).Crossref, Medline, Google Scholar
• 34 Juris S. Biodegradable polysaccharide gels for skin scaffolds. J. Biomater. Nanobiotechnol. 2(3), 216–225 (2011).Crossref, CAS, Google Scholar
• 35 Dinah F, Adhikari A. Gauze packing of open surgical wounds: empirical or evidence-based practice? Ann. R. Coll. Surg. Engl. 88(1), 33–36 (2006).Crossref, Medline, CAS, Google Scholar
• 36 Jones V, Grey JE, Harding KG. Wound dressings. BMJ 332, 777–780 (2006).Crossref, Medline, Google Scholar
• 37 Martineau L, Shek PN. Evaluation of a bi-layer wound dressing for burn care I. Cooling and wound healing properties. Burns 32(1), 70–76 (2006).Crossref, Medline, Google Scholar
• 38 Dumville JC, Deshpande S, O'Meara S, Speak K. Foam dressings for healing diabetic foot ulcers (review). Cochrane Database Syst. Rev. 9, CD009111 (2011).Medline, Google Scholar
• 39 Vowden K, Vowden P. Wound dressings: principles and practice. Surgery 32(9), 462–467 (2014).Google Scholar
• 40 Blaine MG. Experimental observations on absorbable. Ann. Surg. 125, 102–114 (1946).Crossref, Google Scholar
• 41 Weller C, Sussman G. Wound dressings update. J. Pharm. Pract. Res. 36(4), 39–42 (2006).Crossref, Google Scholar
• 42 Gilchrist T, Martin a M. Wound treatment with sorbsan – an alginate fibre dressing. Biomaterials 4, 317–320 (1983).Crossref, Medline, CAS, Google Scholar
• 43 Dumville JC, O'Meara S, Deshpande S, Speak K. Hydrogel dressings for healing diabetic foot ulcers (review). Cochrane Database Syst. Rev. 9(7), 1–48 (2013).Google Scholar
• 44 Thomas S, Loveless P. A comparative study of the properties of twelve hydrocolloid dressings. World Wide Wounds 1997, 1–10 (1997).Google Scholar
• 45 Angel D, Morey P, Storer J, Mwipatayi B. The great debate over iodine in wound care continues: a review of the literature. Wound Pract. Res. J. Aust. Wound Manag. Assoc. 16(1), 6–21 (2008).Google Scholar
• 46 Sibbald R, Leaper D, Queen D. Iodine made easy. Wounds Int. 2(2), 1–6 (2011).Google Scholar
• 47 Cooper RA. Iodine revisited. Int. Wound J. 4(2), 124–137 (2007).Crossref, Medline, Google Scholar
• 48 Wei L, Tang J, Zhang Z, Chen Y, Zhou G, Xi T. Investigation of the cytotoxicity mechanism of silver nanoparticles in vitro. Biomed. Mater. 5(4), 044103 (2010).Crossref, Medline, Google Scholar
• 49 Poon VKM, Burd A. In vitro cytotoxity of silver: implication for clinical wound care. Burns 30(2), 140–147 (2004).Crossref, Medline, Google Scholar
• 50 Leaper DJ. Silver dressings: their role in wound management. Int. Wound J. 3(4), 282–294 (2006).Crossref, Medline, Google Scholar
• 51 Li CW, Fu RQ, Yu CP et al. Silver nanoparticle/chitosan oligosaccharide/poly(vinyl alcohol) nanofibers as wound dressings: a preclinical study. Int. J. Nanomed. 8, 4131–4145 (2013).Medline, Google Scholar
• 52 Zhang Y, Lim CT, Ramakrishna S, Huang Z-M. Recent development of polymer nanofibers for biomedical and biotechnological applications. J. Mater. Sci. Mater. Med. 16(10), 933–946 (2005).Crossref, Medline, CAS, Google Scholar
• 53 Gholipour Kanani A, Hajir Bahrami S. Review on electrospun nanofibres scaffold and biomedical applications. Trends Biomater. Artif. Organs 24(2), 93–115 (2010).Google Scholar
• 54 Martindale D. Scar no more. Sci. Am. 283, 34–36 (2000).CAS, Google Scholar
• 55 Jannesari M, Varshosaz J, Morshed M, Zamani M. Composite poly(vinyl alcohol)/poly(vinyl acetate) electrospun nanofibrous mats as a novel wound dressing matrix for controlled release of drugs. Int. J. Nanomed. 6, 993–1003 (2011).Medline, CAS, Google Scholar
• 56 Dicks LMT, Heunis TDJ. Nanofibers offer alternative ways to the treatment of skin infections. J. Biomed. Biotechnol. 2010, pii: 510682 (2010).Medline, Google Scholar
• 57 Nayak R, Padhye R, Kyratzis IL, Truong YB, Arnold L. Recent advances in nanofibre fabrication techniques. Text Res. J. 82(2), 129–147 (2012).Crossref, CAS, Google Scholar
• 58 Hartgerink JD, Beniash E, Stupp SI. Self-assembly and mineralization of peptide-amphiphile nanofibers. Science 294(5547), 1684–1688 (2001).Crossref, Medline, CAS, Google Scholar
• 59 Luo C, Stoyanov S, Stride E, Pelan E, Edirisinghe M. Electrospinning versus fibre production methods: from specifics to technological convergence. Chem. Soc. Rev. 41(13), 4708–4735 (2012).Crossref, Medline, CAS, Google Scholar
• 60 Khan N. Applications of electrospun nanofibers in the biomedical field. SURG 5(2), 63–73 (2012).Crossref, Google Scholar
• 61 Kanani a G, Bahrami SH. Review on electrospun nanofibres scaffold and biomedical applications. Trends Biomater. Artif. Organs 24(2), 93–115 (2010).Google Scholar
• 62 Haghi AK, Akbari M. Trends in electrospinning of natural nanofibers. Physica Status Solidi A. Appl. Res. 204(6), 1830–1834 (2007).CAS, Google Scholar
• 63 Sukigara S, Gandhi M, Ayutsede J, Micklus M, Ko F. Regeneration of Bombyx mori silk by electrospinning–part 1: processing parameters and geometric properties. Polymer (Guildf.) 44(19), 5721–5727 (2003).Crossref, CAS, Google Scholar
• 64 Tan EPS, Ng SY, Lim CT. Tensile testing of a single ultrafine polymeric fiber. Biomaterials 26(13), 1453–1456 (2005).Crossref, Medline, CAS, Google Scholar
• 65 Pillay V, Dott C, Choonara YE et al. A review of the effect of processing variables on the fabrication of electrospun nanofibers for drug delivery applications. J. Nanomater. 2013, 789289 (2013).Crossref, Google Scholar
• 66 Bhardwaj N, Kundu SC. Electrospinning: a fascinating fiber fabrication technique. Biotechnol. Adv. 28(3), 325–347 (2010).Crossref, Medline, CAS, Google Scholar
• 67 Pham QP, Sharma U, Mikos AG. Electrospun poly(epsilon-caprolactone) microfiber and multilayer nanofiber/microfiber scaffolds: characterization of scaffolds and measurement of cellular infiltration. Biomacromolecules 7(10), 2796–2805 (2006).Crossref, Medline, CAS, Google Scholar
• 68 Zhang C, Yuan X, Wu L, Han Y, Sheng J. Study on morphology of electrospun poly(vinyl alcohol) mats. Eur. Polym. J. 41(3), 423–432 (2005).Crossref, CAS, Google Scholar
• 69 Ki CS, Baek DH, Gang KD, Lee KH, Um IC, Park YH. Characterization of gelatin nanofiber prepared from gelatin-formic acid solution. Polymer (Guildf.) 46(14), 5094–5102 (2005).Crossref, CAS, Google Scholar
• 70 Geng X, Kwon OH, Jang J. Electrospinning of chitosan dissolved in concentrated acetic acid solution. Biomaterials 26(27), 5427–5432 (2005).Crossref, Medline, CAS, Google Scholar
• 71 Zhao Z, Li J, Yuan X, Li X, Zhang Y, Sheng J. Preparation and properties of electrospun poly(vinylidene fluoride) membranes. J. Appl. Polym. Sci. 97(2), 466–474 (2005).Crossref, CAS, Google Scholar
• 72 Yuan XY, Zhang YY, Dong C, Sheng J. Morphology of ultrafine polysulfone fibers prepared by electrospinning. Polym. Int. 53(11), 1704–1710 (2004).Crossref, CAS, Google Scholar
• 73 Kim KH, Jeong L, Park HN et al. Biological efficacy of silk fibroin nanofiber membranes for guided bone regeneration. J. Biotechnol. 120(3), 327–339 (2005).Crossref, Medline, CAS, Google Scholar
• 74 Wannatong L, Sirivat A, Supaphol P. Effects of solvents on electrospun polymeric fibers: preliminary study on polystyrene. Polym. Int. 53(11), 1851–1859 (2004).Crossref, CAS, Google Scholar
• 75 Sundaray B, Subramanian V, Natarajan TS, Xiang RZ, Chang CC, Fann WS. Electrospinning of continuous aligned polymer fibers. Appl. Phys. Lett. 84(7), 1222–1224 (2004).Crossref, CAS, Google Scholar
• 76 Li D, Xia Y. Electrospinning of nanofibers: reinventing the wheel? Adv. Mater. 16(14), 1151–1170 (2004).Crossref, CAS, Google Scholar
• 77 Xu CY, Inai R, Kotaki M, Ramakrishna S. Aligned biodegradable nanofibrous structure: a potential scaffold for blood vessel engineering. Biomaterials 25(5), 877–886 (2004).Crossref, Medline, CAS, Google Scholar
• 78 Wang X, Um IC, Fang D, Okamoto A, Hsiao BS, Chu B. Formation of water-resistant hyaluronic acid nanofibers by blowing-assisted electro-spinning and non-toxic post treatments. Polymer (Guildf.) 46(13), 4853–4867 (2005).Crossref, CAS, Google Scholar
• 79 Reneker DH, Chun I. Nanometre diameter fibres of polymer, produced by electrospinning. Nanotechnology 7(3), 216–223 (1999).Crossref, Google Scholar
• 80 Supaphol P, Mit-Uppatham C, Nithitanakul M. Ultrafine electrospun polyamide-6 fibers: effect of emitting electrode polarity on morphology and average fiber diameter. J. Polym. Sci. B Polym. Phys. 43(24), 3699–3712 (2005).Crossref, CAS, Google Scholar
• 81 Casper CL, Stephens JS, Tassi NG, Chase DB, Rabolt JF. Controlling surface morphology of electrospun polystyrene fibers: effect of humidity and molecular weight in the electrospinning process. Macromolecules 37(2), 573–578 (2004).Crossref, CAS, Google Scholar
• 82 Yu D-G, White K, Chatterton N, Li Y, Li L, Wang X. Structural lipid nanoparticles self-assembled from electrospun core–shell polymeric nanocomposites. RSC Adv. 5(13), 9462–9466 (2015).Crossref, CAS, Google Scholar
• 83 Yu D-G, Li X-Y, Wang X, Yang J-H, Bligh SWA, Williams GR. Nanofibers fabricated using triaxial electrospinning as zero order drug delivery systems. ACS Appl. Mater. Interfaces 7(33), 18891–18897 (2015).Crossref, Medline, CAS, Google Scholar
• 84 Cook N. Methicillin-resistant Staphylococcus aureus versus the burn patient. Burns 24(2), 91–98 (1998).Crossref, Medline, CAS, Google Scholar
• 85 Chen G, Xu Y, Yu D-G, Zhang D-F, Chatterton NP, White KN. Structure-tunable Janus fibers fabricated using spinnerets with varying port angles. Chem. Commun. 51(22), 4623–4626 (2015).Crossref, Medline, CAS, Google Scholar
• 86 Li L, Hsieh Y Lo. Chitosan bicomponent nanofibers and nanoporous fibers. Carbohydr. Res. 341(3), 374–381 (2006).Crossref, Medline, CAS, Google Scholar
• 87 Pakravan M, Heuzey MC, Ajji A. A fundamental study of chitosan/PEO electrospinning. Polymer (Guildf.) 52(21), 4813–4824 (2011).Crossref, CAS, Google Scholar
• 88 Charernsriwilaiwat N, Rojanarata T, Ngawhirunpat T, Opanasopit P. Electrospun chitosan/polyvinyl alcohol nanofibre mats for wound healing. Int. Wound J. 11(2), 215–222 (2014).Crossref, Medline, Google Scholar
• 89 Naseri N, Algan C, Jacobs V, John M, Oksman K, Mathew AP. Electrospun chitosan-based nanocomposite mats reinforced with chitin nanocrystals for wound dressing. Carbohydr. Polym. 109, 7–15 (2014).Crossref, Medline, CAS, Google Scholar
• 90 Ki CS, Park YH, Jin H-J. Silk protein as a fascinating biomedical polymer: structural fundamentals and applications. Macromol. Res. 17(12), 935–942 (2009).Crossref, CAS, Google Scholar
• 91 Padamwar MN, Pawar AP. Silk sericin and its applications: a review. J. Sci. Ind. Res. (India) 63(4), 323–329 (2004).CAS, Google Scholar
• 92 Vasconcelos A, Freddi G, Cavaco-Paulo A. Biodegradable materials based on silk fibroin and keratin. Biomacromolecules 9(4), 1299–1305 (2008).Crossref, Medline, CAS, Google Scholar
• 93 Shahverdi S, Hajimiri M, Esfandiari MA et al. Fabrication and structure analysis of poly(lactide-co-glycolic acid)/silk fibroin hybrid scaffold for wound dressing applications. Int. J. Pharm. 473(1–2), 345–355 (2014).Crossref, Medline, CAS, Google Scholar
• 94 Çalamak S, Erdoğdu C, Özalp M, Ulubayram K. Silk fibroin based antibacterial bionanotextiles as wound dressing materials. Mater. Sci. Eng. C. 43, 11–20 (2014).Crossref, Medline, CAS, Google Scholar
• 95 Yang D, Li Y, Nie J. Preparation of gelatin/PVA nanofibers and their potential application in controlled release of drugs. Carbohydr. Polym. 69(3), 538–543 (2007).Crossref, CAS, Google Scholar
• 96 Ulubayram K, Aksu E, Gurhan SID, Serbetci K, Hasirci N. Cytotoxicity evaluation of gelatin sponges prepared with different cross-linking agents. J. Biomater. Sci. Polym. Ed. 13(11), 1203–1219 (2002).Crossref, Medline, CAS, Google Scholar
• 97 Gu SY, Wang ZM, Ren J, Zhang CY. Electrospinning of gelatin and gelatin/poly(l-lactide) blend and its characteristics for wound dressing. Mater. Sci. Eng. C. 29(6), 1822–1828 (2009).Crossref, CAS, Google Scholar
• 98 Ki CS, Baek DH, Gang KD, Lee KH, Um IC, Park YH. Characterization of gelatin nanofiber prepared from gelatin–formic acid solution. Polymer (Guildf.) 46(14), 5094–5102 (2005).Crossref, CAS, Google Scholar
• 99 Huang Z-M, Zhang Y, Ramakrishna S, Lim C. Electrospinning and mechanical characterization of gelatin nanofibers. Polymer (Guildf.) 45(15), 5361–5368 (2004).Crossref, CAS, Google Scholar
• 100 Songchotikunpan P, Tattiyakul J, Supaphol P. Extraction and electrospinning of gelatin from fish skin. Int. J. Biol. Macromol. 42(3), 247–255 (2008).Crossref, Medline, CAS, Google Scholar
• 101 Zhang YZ, Venugopal J, Huang ZM, Lim CT, Ramakrishna S. Crosslinking of the electrospun gelatin nanofibers. Polymer (Guildf.) 47, 2911–2917 (2006).Crossref, CAS, Google Scholar
• 102 Li M, Mondrinos MJ, Gandhi MR, Ko FK, Weiss AS, Lelkes PI. Electrospun protein fibers as matrices for tissue engineering. Biomaterials 26(30), 5999–6008 (2005).Crossref, Medline, CAS, Google Scholar
• 103 Lu W, Ma M, Xu H, Zhang B, Cao X, Guo Y. Gelatin nano fibers prepared by spiral-electrospinning and cross-linked by vapor and liquid-phase glutaraldehyde. Mater. Lett. 140, 1–4 (2015).Crossref, CAS, Google Scholar
• 104 Kang YO, Yoon IS, Lee SY et al. Chitosan-coated poly(vinyl alcohol) nanofibers for wound dressings. J. Biomed. Mater. Res. B Appl. Biomater. 92(2), 568–576 (2010).Medline, Google Scholar
• 105 Li X, Kanjwal MA, Lin L, Chronakis IS. Electrospun polyvinyl-alcohol nanofibers as oral fast-dissolving delivery system of caffeine and riboflavin. Colloids Surf. B Biointerfaces 103, 182–188 (2013).Crossref, Medline, CAS, Google Scholar
• 106 Kadri NA, Raha MG, Pingguan-Murphy B. Polyvinyl alcohol as a viable membrane in artificial tissue design and development. Clinics (Sao Paulo) 66(8), 1489–1494 (2011).Crossref, Medline, Google Scholar
• 107 Kamoun EA, Chen X, Mohy Eldin MS, Kenawy ERS. Crosslinked poly(vinyl alcohol) hydrogels for wound dressing applications: a review of remarkably blended polymers. Arabian J. Chem. 8(1), 1–14 (2014).Crossref, Google Scholar
• 108 O'Mahony J, O'Donoghue M, Morgan JG, Hill C. Rotavirus survival and stability in foods as determined by an optimised plaque assay procedure. Int. J. Food Microbiol. 61(2–3), 177–185 (2000).Crossref, Medline, Google Scholar
• 109 Moghbel A, Agheli H, Kalantari E, Naji M. Design and formulation of tragacanth dressing bandage for burn healing with no dermal toxicity. Toxicol. Lett. 180, S154 (2008).Crossref, Google Scholar
• 110 Siahi MR, Barzegar-Jalali M, Monajjemzadeh F, Ghaffari F, Azarmi S. Design and evaluation of 1- and 3-layer matrices of verapamil hydrochloride for sustaining its release. AAPS Pharm. Sci. Tech. 6(4), E626–E632 (2005).Crossref, Medline, Google Scholar
• 111 Ranjbar-Mohammadi M, Bahrami SH, Joghataei MT. Fabrication of novel nanofiber scaffolds from gum tragacanth/poly(vinyl alcohol) for wound dressing application: in vitro evaluation and antibacterial properties. Mater. Sci. Eng. C. 33(8), 4935–4943 (2013).Crossref, Medline, CAS, Google Scholar
• 112 Rouse JG, Van Dyke ME. A review of keratin-based biomaterials for biomedical applications. Materials (Basel) 3(2), 999–1014 (2010).Crossref, Google Scholar
• 113 Park M, Shin HK, Panthi G et al. Novel preparation and characterization of human hair-based nanofibers using electrospinning process. Int. J. Biol. Macromol. 76, 45–48 (2015).Crossref, Medline, CAS, Google Scholar
• 114 Gökmeşe F, Uslu İ, Aytimur A. Preparation and characterization of PVA/PVP nanofibers as promising materials for wound dressing. Polym. Plast. Technol. Eng. 52(12), 1259–1265 (2013).Crossref, CAS, Google Scholar
• 115 McDonnell G, Russelll D. Antiseptics and disinfectants: activity, action, and resistance. Am. Soc. Microbiol. 12(1), 147–179 (1999).CAS, Google Scholar
• 116 Aytimur A, Uslu İ. Promising materials for wound dressing: PVA/PAA/PVP electrospun nanofibers. Polym. Plast. Technol. Eng. 53(7), 655–660 (2014).Crossref, CAS, Google Scholar
• 117 Aytimur A, Koçyiğit S, Uslu İ. Synthesis and characterization of poly(vinyl alcohol)/poly(vinyl pyrrolidone)-iodine nanofibers with poloxamer 188 and chitosan. Polym. Plast. Technol. Eng. 52(7), 661–666 (2013).Crossref, CAS, Google Scholar
• 118 Lee RC, River LP, Pan FS, Ji L, Wollmann RL. Surfactant-induced sealing of electropermeabilized skeletal muscle membranes in vivo. Proc. Natl Acad. Sci. USA 89(10), 4524–4528 (1992).Crossref, Medline, CAS, Google Scholar
• 119 Abdelaal MY, Makki MSI, Sobahi TRA. Modification and characterization of polyacrylic acid for metal ion recovery. Am. J. Polym. Sci. 2(4), 73–78 (2012).Crossref, Google Scholar
• 120 Pinto MCC, Gomes FW, Melo CK, Melo PA, Castro M, Pinto JC. Production of poly(acrylic acid) particles dispersed in organic media. Macromol. Symp. 319(1), 15–22 (2012).Crossref, CAS, Google Scholar
• 121 Aytimur A, Koçyiğit S, Uslu İ, Gökmeşe F. Preparation and characterization of polyvinyl alcohol based copolymers as wound dressing fibers. Int. J. Polym. Mater. Polym. Biomater. 64(3), 111–116 (2014).Crossref, Google Scholar
• 122 Tsou TL, Tang ST, Huang YC, Wu JR, Young JJ, Wang HJ. Poly(2-hydroxyethyl methacrylate) wound dressing containing ciprofloxacin and its drug release studies. J. Mater. Sci. Mater. Med. 16(2), 95–100 (2005).Crossref, Medline, CAS, Google Scholar
• 123 Hartwell R, Leung V, Chavez-Munoz C et al. A novel hydrogel-collagen composite improves functionality of an injectable extracellular matrix. Acta Biomater. 7(8), 3060–3069 (2011).Crossref, Medline, CAS, Google Scholar
• 124 Sill TJ, von Recum HA. Electrospinning: applications in drug delivery and tissue engineering. Biomaterials 29(13), 1989–2006 (2008).Crossref, Medline, CAS, Google Scholar
• 125 Jiang Q. Natural forms of vitamin E: metabolism, antioxidant, and anti-inflammatory activities and their role in disease prevention and therapy. Free Radic. Biol. Med. 72, 76–90 (2014).Crossref, Medline, CAS, Google Scholar
• 126 Sheng X, Fan L, He C, Zhang K, Mo X, Wang H. Vitamin E-loaded silk fibroin nanofibrous mats fabricated by green process for skin care application. Int. J. Biol. Macromol. 56, 49–56 (2013).Crossref, Medline, CAS, Google Scholar
• 127 Ulubayram K, Cakar AN, Korkusuz P, Ertan C, Hasirci N. EGF containing gelatin-based wound dressings. Biomaterials 22(11), 1345–1356 (2001).Crossref, Medline, CAS, Google Scholar
• 128 Choi JS, Leong KW, Yoo HS. In vivo wound healing of diabetic ulcers using electrospun nanofibers immobilized with human epidermal growth factor (EGF). Biomaterials 29(5), 587–596 (2008).Crossref, Medline, CAS, Google Scholar
• 129 Schiffman JD, Wang Y, Giannelis EP, Elimelech M. Biocidal activity of plasma modified electrospun polysulfone mats functionalized with polyethyleneimine-capped silver nanoparticles. Langmuir 27(21), 13159–13164 (2011).Crossref, Medline, CAS, Google Scholar
• 130 Lakshman L, Shalumon KT, Nair S, Jayakumar R, Nair SV. Preparation of silver nanoparticles incorporated electrospun polyurethane nano-fibrous mat for wound dressing. J. Macromol. Sci. A 47(10), 1012–1018 (2010).Crossref, CAS, Google Scholar
• 131 Nguyen TH, Kim YH, Song HY, Lee BT. Nano Ag loaded PVA nano-fibrous mats for skin applications. J. Biomed. Mater. Res. B Appl. Biomater. 96B(2), 225–233 (2011).Crossref, CAS, Google Scholar
• 132 Wilkinson LJ, White RJ, Chipman JK. Silver and nanoparticles of silver in wound dressings: a review of efficacy and safety. J. Wound Care 20(11), 543–549 (2011).Crossref, Medline, CAS, Google Scholar
• 133 Wong KKY, Cheung SOF, Huang L et al. Further evidence of the anti-inflammatory effects of silver nanoparticles. Chem Med Chem 4(7), 1129–1135 (2009).Crossref, CAS, Google Scholar
• 134 Azad A-M, Hershey R, Ali S, Goel V. Bactericidal efficacy of electrospun pure and Fe-doped titania nanofibers. J. Mater. Res. 25(09), 1761–1770 (2010).Crossref, CAS, Google Scholar
• 135 Yan L, Si S, Chen Y et al. Electrospun in-situ hybrid polyurethane/nano-TiO2 as wound dressings. Fibers Polym. 12(2), 207–213 (2011).Crossref, CAS, Google Scholar
• 136 Amna T, Hassan MS, Barakat NAM et al. Antibacterial activity and interaction mechanism of electrospun zinc-doped titania nanofibers. Appl. Microbiol. Biotechnol. 93(2), 743–751 (2012).Crossref, Medline, CAS, Google Scholar
• 137 Shalumon KT, Anulekha KH, Nair SV, Nair SV, Chennazhi KP, Jayakumar R. Sodium alginate/poly(vinyl alcohol)/nano ZnO composite nanofibers for antibacterial wound dressings. Int. J. Biol. Macromol. 49(3), 247–254 (2011).Crossref, Medline, CAS, Google Scholar
• 138 Khalil KA, Fouad H, Elsarnagawy T, Almajhdi FN. Preparation and characterization of electrospun PLGA/silver composite nanofibers for biomedical applications. Int. J. Electrochem. Sci. 8, 3483–3493 (2013).Google Scholar
• 139 Unnithan AR, Barakat NAM, Tirupathi Pichiah PB et al. Wound-dressing materials with antibacterial activity from electrospun polyurethane–dextran nanofiber mats containing ciprofloxacin HCl. Carbohydr. Polym. 90(4), 1786–1793 (2012).Crossref, Medline, CAS, Google Scholar
• 140 Sabitha M, Rajiv S. Synthesis and characterization of biocompatible tigecycline imbibed electrospun poly ε-caprolactone urethane urea fibers. RSC Adv. 5(3), 2249–2257 (2015).Crossref, CAS, Google Scholar
• 141 Cheng F, Gao J, Wang L, Hu X. Composite chitosan/poly(ethylene oxide) electrospun nanofibrous mats as novel wound dressing matrixes for the controlled release of drugs. J. Appl. Polym. Sci. 132(24), 42060 (2015).Crossref, Google Scholar
• 142 Fu S-Z, Meng X-H, Fan J et al. Acceleration of dermal wound healing by using electrospun curcumin-loaded poly(ε-caprolactone)-poly(ethylene glycol)-poly(ε-caprolactone) fibrous mats. J. Biomed. Mater. Res. B Appl. Biomater. 102(3), 533–542 (2014).Crossref, Medline, Google Scholar
• 143 Duman M, Şendemir Ürkmez A, Zeybek B. Electrospinning of nanofibrous polycaprolactone (PCL) and collagen-blended polycaprolactone for wound dressing and tissue engineering. Usak. Univ. J. Mater. Sci. 3(1), 121–121 (2014).Google Scholar
• 144 Motealleh B, Zahedi P, Rezaeian I, Moghimi M, Abdolghaffari AH, Zarandi MA. Morphology, drug release, antibacterial, cell proliferation, and histology studies of chamomile-loaded wound dressing mats based on electrospun nanofibrous poly(ε-caprolactone)/polystyrene blends. J. Biomed. Mater. Res. B Appl. Biomater. 102(5), 977–987 (2014).Crossref, Medline, Google Scholar
• 145 Karami Z, Rezaeian I, Zahedi P, Abdollahi M. Preparation and performance evaluations of electrospun poly(ε-caprolactone), poly(lactic acid), and their hybrid (50/50) nanofibrous mats containing thymol as an herbal drug for effective wound healing. J. Appl. Polym. Sci. 129(2), 756–766 (2013).Crossref, CAS, Google Scholar