We use cookies to improve your experience. By continuing to browse this site, you accept our cookie policy.×
Skip main navigation
Aging Health
Bioelectronics in Medicine
Biomarkers in Medicine
Breast Cancer Management
CNS Oncology
Colorectal Cancer
Concussion
Epigenomics
Future Cardiology
Future Medicine AI
Future Microbiology
Future Neurology
Future Oncology
Future Rare Diseases
Future Virology
Hepatic Oncology
HIV Therapy
Immunotherapy
International Journal of Endocrine Oncology
International Journal of Hematologic Oncology
Journal of 3D Printing in Medicine
Lung Cancer Management
Melanoma Management
Nanomedicine
Neurodegenerative Disease Management
Pain Management
Pediatric Health
Personalized Medicine
Pharmacogenomics
Regenerative Medicine

How can nanoparticles be used to overcome the challenges of glaucoma treatment?

    Subbu Venkatraman

    Author for correspondence:

    E-mail Address: assubbu@ntu.edu.sg

    School of Materials Science & Engineering, NTU & Ocular Therapeutic Engineering Centre, NTU, 50 Nanyang Avenue, 639798 Singapore 

    &
    Tina Wong

    Singapore National Eye Centre & Ocular Therapeutic Engineering Centre, NTU, 50 Nanyang Avenue, 639798 Singapore

    Published Online:https://doi.org/10.2217/nnm.14.85
    Free first page

    References

    • 1 Quigley AH, Broman AT. The number of people with glaucoma worldwide in 2010 and 2020. Br. J. Ophthalmol. 90, 262–267 (2006).
    • 2 Tan YF, Mundargi RC, Chen MHA et al. Layer-by-layer nanoparticles as an efficient siRNA delivery vehicle for SPARC silencing. Small 10(9), 1790–1798 (2014).
    • 3 Ciolino JB, Stefanescu CF, Ross AE et al. In vivo performance of a drug-eluting contact lens to treat glaucoma for a month. Biomaterials 35, 432–439 (2014).
    • 4 Chong RS, Su DH, Tsai A et al. Patient acceptance and attitude toward an alternative method of subconjunctival injection for the medical treatment of glaucomaJ. Glaucoma. 22(3), 190–194 (2013).
    • 5 Jayaganesh NV, Darwitan A, Barathi VA et al. Sustained drug release in nanomedicine: a long-acting nanocarrier-based formulation for glaucoma. ACS Nano 8(1), 419–429 (2014).
    • 6 Wong TT, Novack GD, Ho CL, Jayaganesh NV, Htoon HM, Venkatraman SSNanomedicine for glaucoma: sustained release latanoprost offers a new therapeutic option with substantial benefits over eye dropsDrug Deliv. Transl. Res. 4(4), 303–309 (2014).
    • 7 Abrishami M, Ganavati SZ, Soroush D, Rouhbaksh M, jaafari MR, Malaekeh-Nikouei: Preparation, characterization and in vivo evaluation of nanoliposomes-encapsulated bevacizumab (Avastin) for intravitreal administration. Retina 29, 699–703 (2009).
    • 8 Honda M, Asai T, Oku N, Tanaka M, Ebihara N. Liposomes and nanotechnology in drug development: focus on ocular therapies. Int. J. Nanomedicine 8, 495–504 (2013).
    • 9 pSivida Corp. www.psivida.com/products-iluvien.html