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Ask the Experts: How important is radiofrequency ablation in lung cancer?

    Terrance T Healey

    * Author for correspondence

    Department of Diagnostic Imaging, Warren Alpert Medical School of Brown University, Rhode Island Hospital, 593 Eddy St, Providence, RI 02903, USA. .

    ,
    Robert C Ward

    Department of Diagnostic Imaging, Warren Alpert Medical School of Brown University, Rhode Island Hospital, 593 Eddy St, Providence, RI 02903, USA

    &
    Damian E Dupuy

    Department of Diagnostic Imaging, Warren Alpert Medical School of Brown University, Rhode Island Hospital, 593 Eddy St, Providence, RI 02903, USA

    Published Online:https://doi.org/10.2217/lmt.13.24

    Terrance T Healey is the director of Thoracic Radiology at Rhode Island Hospital (RI, USA) and an Assistant Professor of Diagnostic Imaging at the Alpert Medical School of Brown University (RI, USA). Healey received his medical degree from the combined Dartmouth Medical School–Brown Medical School Program in 2003, completed his residency in radiology at Brown University in 2008 and a thoracic radiology fellowship at the Massachusetts General Hospital (MA, USA) in 2009. He joined the faculty staff at Rhode Island Hospital and Brown University in 2009.

    Robert C Ward is one of the chief residents within the Department of Diagnostic Imaging at Rhode Island Hospital (RI, USA) and the Alpert Medical School of Brown University (RI, USA). Ward received his medical degree from the George Washington University (Washington, DC, USA) in 2010.

    Damian E Dupuy is the director of Tumor Ablation at Rhode Island Hospital (RI, USA) and a Professor of Diagnostic Imaging at The Warren Alpert Medical School of Brown University (RI, USA). Dupuy received his medical degree from the University of Massachusetts Medical School (MA, USA) in 1988 and completed his residency in radiology at The New England Deaconess Hospital (MA, USA) and Harvard Medical School (MA, USA) in 1993. After residency, Dupuy joined the staff at Massachusetts General Hospital (MA, USA) where he worked in the Abdominal Imaging and Bone and Joint Divisions. In 1997, Dupuy joined the Department of Diagnostic Imaging at Rhode Island Hospital and Brown University. Dupuy, a pioneer in the use of image-guided ablation, helped broaden clinical applications to successfully combat cancer involving the kidney, liver, lung, head and neck, adrenal gland and skeleton. Other newer technologies, such as percutaneous microwave ablation, cryoablation and combination therapies using radiofrequency ablation with external radiation or brachytherapy, have been pioneered by Dupuy who has been the principal investigator of two National Cancer Institute-funded multicenter trials. Dupuy has received national awards for research and teaching from the American College of Radiology Imaging Network and the Radiological Society of North America where he is currently the Chair of the Interventional Oncology Symposium featured at the Annual Meeting of the Radiological Society of North America and a Fellow of the American College of Radiology. Dupuy is a member of the Radiological Society of North America, The New England Roentgen Ray Society, The American College of Radiology, Rhode Island Radiological Society and the Society of Interventional Radiology. Dupuy has published over 150 publications and given over 120 invited lectures in the field of radiology and image-guided ablation, both nationally and internationally.

    References

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    • Healey TT, Dupuy DE. Radiofrequency ablation: a safe and effective treatment in nonoperative patients with early-stage lung cancer. Cancer J.17(1),33–37 (2011).
    • Dupuy DE. Image-guided thermal ablation of lung malignancies. Radiology260(3),633–655 (2011).
    • Simon CJ, Dupuy DE, DiPetrillo TA et al. Pulmonary radiofrequency ablation: long-term safety and efficacy in 153 patients. Radiology243(1),268–275 (2007).
    • Lencioni R, Crocetti L, Cioni R et al. Response to radiofrequency ablation of pulmonary tumours: a prospective, intention-to-treat, multicentre clinical trial (the RAPTURE study). Lancet Oncol.9(7),621–628 (2008).
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    • 10  Alexander ES, Hankins CA, Machan JT, Healey TT, Dupuy DE. Rib fractures after percutaneous radiofrequency and microwave ablation of lung tumors: incidence and relevance. Radiology266(3),971–978 (2013).
    • 11  Alexander ES, Healey TT, Martin DW, Dupuy DE. Use of endobronchial valves for the treatment of bronchopleural fistulas after thermal ablation of lung neoplasms. J. Vasc. Interv. Radiol.23(9),1236–1240 (2012).