RAB27A is an independent prognostic factor in clear cell renal cell carcinoma

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References

• 1 Zerial M, McBride H. Rab proteins as membrane organizers. Nat. Rev. Mol. Cell Biol. 2(2), 107 (2001). • Recent review of main concepts and definition of Rab GTPase.Crossref, Medline, CAS, Google Scholar
• 2 Ostrowski M, Carmo NB, Krumeich S et al. Rab27a and Rab27b control different steps of the exosome secretion pathway. Nat. Cell Biol. 12(1), 19 (2010). •• Key article on RAB27A and RAB27B secretion pathway.Crossref, Medline, CAS, Google Scholar
• 3 Fukuda M. Regulation of secretory vesicle traffic by Rab small GTPases. Cell Mol. Life Sci. 65(18), 2801–2813 (2008).Crossref, Medline, CAS, Google Scholar
• 4 Seabra MC, Mules EH, Hume AN. Rab GTPases, intracellular traffic and disease. Trends Mol. Med. 8(1), 23–30 (2002).Crossref, Medline, CAS, Google Scholar
• 5 Hutagalung AH, Novick PJ. Role of Rab GTPases in membrane traffic and cell physiology. Physiol. Rev. 91(1), 119–149 (2011).Crossref, Medline, CAS, Google Scholar
• 6 Stenmark H. Rab GTPases as coordinators of vesicle traffic. Nat. Rev. Mol. Cell Biol. 10(8), 513 (2009). • Recent review of the role of Rab GTPase as vesicle transporter.Crossref, Medline, CAS, Google Scholar
• 7 Ostenfeld MS, Jeppesen DK, Laurberg JR et al. Cellular disposal of miR23b by RAB27-dependent exosome release is linked to acquisition of metastatic properties. Cancer Res. 74(20), 5758–5771 (2014). •• An important article demonstrating the cellular disposal of miRNA by RAB27 family.Crossref, Medline, CAS, Google Scholar
• 8 Hendrix A, Braems G, Bracke M et al. The secretory small GTPase Rab27B as a marker for breast cancer progression. Oncotarget 1(4), 304–308 (2010).Crossref, Medline, Google Scholar
• 9 Kumar V, Abbas AK, Fausto N, Aster JC. Robbins and Cotran Pathologic Basis of Disease, (Professional Edition e-book). Elsevier Health Sciences, Philadelpia, PA, USA (2014).Google Scholar
• 10 Volinia S, Calin GA, Liu CG et al. A microRNA expression signature of human solid tumors defines cancer gene targets. Proc. Natl Acad. Sci. USA 103(7), 2257–2261 (2006).Crossref, Medline, CAS, Google Scholar
• 11 Calin GA, Croce CM. MicroRNA signatures in human cancers. Nat. Rev. Cancer 6(11), 857 (2006).Crossref, Medline, CAS, Google Scholar
• 12 Iorio MV, Ferracin M, Liu CG et al. MicroRNA gene expression deregulation in human breast cancer. Cancer Res. 65(16), 7065–7070 (2005).Crossref, Medline, CAS, Google Scholar
• 13 Ono M, Kosaka N, Tominaga N et al. Exosomes from bone marrow mesenchymal stem cells contain a microRNA that promotes dormancy in metastatic breast cancer cells. Sci. Signal. 7(332), ra63–ra63 (2014).Crossref, Medline, Google Scholar
• 14 Pellegrino L, Stebbing J, Braga VM et al. miR-23b regulates cytoskeletal remodeling, motility and metastasis by directly targeting multiple transcripts. Nucl. Acids Res. 41(10), 5400–5412 (2013).Crossref, Medline, CAS, Google Scholar
• 15 Majid S, Dar AA, Saini S et al. miR-23b represses proto-oncogene Src kinase and functions as methylation-silenced tumor suppressor with diagnostic and prognostic significance in prostate cancer. Cancer Res. 72, 6435–6446 (2012). • Key article on microRNA as a tumor suppressor.Crossref, Medline, CAS, Google Scholar
• 16 Zhang H, Hao Y, Yang J et al. Genome-wide functional screening of miR-23b as a pleiotropic modulator suppressing cancer metastasis. Nat. Commun. 2(554), 1–11 (2011).Google Scholar
• 17 Dickman CT, Lawson J, Jabalee J et al. Selective extracellular vesicle exclusion of miR-142-3p by oral cancer cells promotes both internal and extracellular malignant phenotypes. Oncotarget 8(9), 15252–15266 (2017).Crossref, Medline, Google Scholar
• 18 Fukuda M. Versatile role of Rab27 in membrane trafficking: focus on the Rab27 effector families. J. Biochem. 137(1), 9–16 (2005). • One of the first articles that focuses on the RAB27 family.Crossref, Medline, Google Scholar
• 19 Fukuda M. Rab27 and its effectors in secretory granule exocytosis: a novel docking machinery composed of a Rab27 effector complex. Biochem. Soc. Trans. 34(Pt 5), 691–695 (2006).Crossref, Medline, CAS, Google Scholar