Blood supply of the graft after cellular cardiomyoplasty

Papers of special note have been highlighted as:▪  of interest ▪▪ of considerable interest

Bibliography

• 1  Reffelmann T, Kloner RA: Cellular cardiomyoplasty–cardiomyocytes, skeletal myoblasts, or stem cells for regenerating myocardium and treatment of heart failure? Cardiovasc. Res.58,358–368 (2003).
  Medline CASGoogle Scholar
• 2  Forrester JS, White AJ, Matsushita S, Chakravarty T, Makkar RR: New paradigms of myocardial regeneration post-infarction. Tissue preservation, cell environment, and pluripotent cell sources. J. Am. Coll. Cardiol. Interv.2,1–8 (2009).
  MedlineGoogle Scholar
• 3  Forrester JS, Makkar RR, Marbán E: Long-term outcome of stem cell therapy for acute myocardial infarction. Right results, wrong reasons. J. Am. Coll. Cardiol.53,2270–2272 (2009).▪ Interesting discussion of the scientific work of cell transplantation.
  MedlineGoogle Scholar
• 4  Reffelmann T, Könemann S, Kloner RA: Promise of blood- and bone marrow-derived stem cell transplantation for functional cardiac repair. Putting it in perspective with existing therapy. J. Am. Coll. Cardiol.53,305–308 (2009).
  MedlineGoogle Scholar
• 5  Müller-Ehmsen J, Peterson KL, Kedes L et al.: Rebuilding a damaged heart: long-term survival of transplanted neonatal rat cardiomyocates after myocardial infarction and effect on cardiac function. Circulation105,1720–1726 (2002).▪ Long-term follow-up of transplantation of neonatal cardiomyocytes in experimental myocardial infarction.
  MedlineGoogle Scholar
• 6  Taylor DA, Atkins BZ, Hungspreugs P et al.: Regenerating functional myocardium: improved performance after skeletal myoblast transplantation. Nat. Med.4,929–933 (1998).
  Medline CASGoogle Scholar
• 7  Jain M, DerSimonian H, Brenner DA et al.: Cell therapy attenuates deleterious ventricular remodeling and improves cardiac performance after myocardial infarction. Circulation103,1920–1927 (2001).
  Medline CASGoogle Scholar
• 8  Min JY, Yang Y, Converso KL et al.: Transplantation of embryonic stem cells improves cardiac function in postinfarcted rats. J. Appl. Physiol.92,288–296 (2002).
  MedlineGoogle Scholar
• 9  Tomita S, Li RK, Weisel RD et al.: Autologous transplantation of bone marrow cells improves damaged heart function. Circulation100(19 Suppl. 2),II247–II256 (1999).
  Medline CASGoogle Scholar
• 10  Jumaby M, Matsumoto T, Yokoyama S et al.: Dedifferentiated fat cells convert to cardiomyocyte phenotype and repair cardiac tissue in rats. J. Mol. Cell. Cardiol.47,565–575 (2009).
  MedlineGoogle Scholar
• 11  Kocher AA, Schuster MD, Szabolcs MJ et al.: Neovascularization of ischemic myocardium by human bone-marrow-derived angioblasts prevents cardiomyocyte apoptosis, reduces remodeling and improves cardiac function. Nat. Med.7,430–436 (2001).▪▪ Landmark study on angiogenesis after transplantation of bone marrow-derived cells.
  Medline CASGoogle Scholar
• 12  Ramshorst J, Bax JJ, Beeres SL et al.: Intramyocardial bone marrow cell injection for chronic myocardial ischemia. A randomized controlled trial. JAMA301,1997–2004 (2009).▪▪ Systematic randomized trial demonstrating effective reduction of anginal symptoms and perfusion defects by intramyocardial cell transplantation in patients with severe chronic angina pectoris
  MedlineGoogle Scholar
• 13  Tayyareci Y, Sezer M, Umman B et al.: Intracoronary autologous bone marrow-derived mononuclear cell transplantation improves coronary collateral vessel formation and recruitment capacity in patients with ischemic cardiomyopathy: a combined hemodynamic and scintigraphic approach. Angiology59,145–155 (2008).
  MedlineGoogle Scholar
• 14  Korf-Klingebiel M, Kempf T, Sauer T et al.: Bone marrow cells are a rich source of growth factors and cytokines: implications for cell therapy trials after myocardial infarction. Eur. Heart J.29,2851–2858 (2008).
  MedlineGoogle Scholar
• 15  Reffelmann T, Hale SL, Dow JS, Kloner RA: The no-reflow phenomenon persists long term after ischemia reperfusion in the rat, and predicts infarct expansion. Circulation108,2911–2917 (2003).
  MedlineGoogle Scholar
• 16  Rossi MA: Chronic hemodynamic unloading regulates the morphologic development of newborn mouse hearts transplanted into the ear of isogenic adult mice. Am. J. Pathol.141,183–191 (1992).
  Medline CASGoogle Scholar
• 17  Bishop SP, Anderson PG, Tucker DC: Morphological development of the rat heart growing in oculo in the absence of hemodynamic workload. Circ. Res.66,84–102 (1990).
  Medline CASGoogle Scholar
• 18  Zhang M, Methot D, Poppa V, Fujio Y, Walsh K, Murry CE: Cardiomyocyte grafting for cardiac repair: graft cell death and anti-death strategies. J. Mol. Cell. Cardiol.33,907–921 (2001).
  Medline CASGoogle Scholar
• 19  Retuerto MA, Schalch P, Patejunas G et al.: Angiogenic pretreatment improves efficacy of cellular cardiomyoplasty performed with fetal cardiomyocyte implantation. J. Thorac. Cardiovasc. Surg.127,1041–1049 (2004).
  MedlineGoogle Scholar
• 20  Retuerto MA, Beckmann JT, Carbray J et al.: Angiogenic pretreatment to enhance myocardial function after cellular cardiomyoplasty with skeletal myoblasts. J. Thorac. Cardiovasc. Surg.133,478–484 (2007).
  MedlineGoogle Scholar
• 21  Azarnoush K, Maurel A, Sebbah L et al.: Enhancement of the functional benefits of skeletal myoblast transplantation by means of co-administration of hypoxia-inducible factor 1-α. J. Thorac. Cardiovasc. Surg.130,173–179 (2005).
  Medline CASGoogle Scholar
• 22  Yao M, Dieterle T, Hale SL et al.: Long-term outcome of fetal cell transplantation on postinfarction ventricular remodeling and function. J. Mol. Cell. Cardiol.35,661–670 (2003).
  Medline CASGoogle Scholar
• 23  Etzion S, Battler A, Barash IM et al.: Influence of embryonic cardiomyocyte transplantation on the progression of heart failure in a rat model of extensive myocardial infarction. J. Mol. Cell. Cardiol.33,1321–1330 (2001).
  Medline CASGoogle Scholar
• 24  Li RK, Mickle DA, Weisel RD, Zhang J, Mohabeer MK: In vivo survival and function of transplanted rat cardiomyocytes. Circ. Res.78,283–288 (1996).
  Medline CASGoogle Scholar
• 25  Li RK, Mickle DAG, Weisel RD et al.: Natural history of fetal rat cardiomyocytes transplanted into adult rat myocardial scar tissue. Circulation96(9 Suppl. 2),II179–II187 (1997).
  Google Scholar
• 26  Müller-Ehmsen J, Whittaker P, Kloner RA et al.: Survival and development of neonatal rat cardiomyocytes transplanted into adult myocardium. J. Mol. Cell. Cardiol.34,107–116 (2002).
  Medline CASGoogle Scholar
• 27  Skobel E, Schuh A, Schwarz ER et al.: Transplantation of fetal cardiomyocytes into infarcted rat hearts results in long-term functional improvement. Tissue Eng.10,849–864 (2004).
  MedlineGoogle Scholar
• 28  Reffelmann T, Dow JS, Dai W, Hale SL, Simkhovich BZ, Kloner RA: Transplantation of neonatal cardiomyocytes after permanent coronary artery occlusion increases regional myocardial blood flow of infarcted myocardium. J. Mol. Cell. Cardiol.35,607–613 (2003).
  Medline CASGoogle Scholar
• 29  Schuh A, Breuer S, Al Dashti R et al.: Administration of vascular endothelial growth factor adjunctive to fetal cardiomyocyte transplantation and improvement of cardiac function in the rat model. J. Cardiovasc. Pharmacol. Ther.10,55–66 (2005).
  Medline CASGoogle Scholar
• 30  Schwarz ER, Speakman MT, Patterson M et al.: Evaluation of the effects of intramyocardial injection of DNA expressing vascular endothelial growth factor (VEGF) in a myocardial infarction model in the rat – angiogenesis and angioma formation. J. Am. Coll. Cardiol.35,1323–1330 (2000).
  Medline CASGoogle Scholar
• 31  Miyagawa S, Sawa Y, Taketani S et al.: Myocardial regeneration therapy for heart failure: hepatocyte growth factor enhances the effect of cellular cardiomyoplasty. Circulation105,2556–2561 (2002).▪ Systematic study suggesting that adjunctive application of HGF could improve results of cell transplantation.
  Medline CASGoogle Scholar
• 32  Ghostine S, Carrion C, Souza LC et al.: Long-term efficacy of myoblast transplantation on regional structure and function after myocardial infarction. Circulation106(12 Suppl. 1),I131–I136 (2002).▪ Long-term follow-up after transplantation of skeletal myoblasts.
  MedlineGoogle Scholar
• 33  Perez-Ilzarbe M, Agbulut O, Pelacho B et al.: Characterization of the paracrine effects of human skleletal myoblasts transplanted in infarcted myocardium. Eur. J. Heart Fail.10,1065–1072 (2008).
  Medline CASGoogle Scholar
• 34  Xia JH, Xie AN, Zhang KL, Xu L, Zheng XY: The vascular endothelial growth factor expression and vascular regeneration in infarcted myocardium by skeletal muscle satellite cells. Chin. Med. J.119,117–121 (2006).
  Medline CASGoogle Scholar
• 35  Memon IA, Sawa Y, Miyagawa S, Taketani S, Matsuda H: Combined autologous cellular cardiomyoplasty with skeletal myoblasts and bone marrow cells in canine hearts for ischemic cardiomyopathy. J. Thorac. Cardiovasc. Surg.130,646–653 (2005).
  MedlineGoogle Scholar
• 36  Asahara T, Murohara T, Sullivan A et al.: Isolation of putative progenitor endothelial cells for angiogenesis. Science275,964–967 (1997).▪▪ Landmark study demonstrating the existence of endothelial progenitor cell.
  Medline CASGoogle Scholar
• 37  Asahara T, Masuda H, Takahashi T et al.: Bone marrow origin of endothelial progenitor cells responsible for postnatal vasculogenesis in physiological and pathological neovascularization. Circ. Res.85,221–228 (1999).
  Medline CASGoogle Scholar
• 38  Shi Q, Rafii S, Wu MH et al.: Evidence for circulating bone marrow-derived endothelial cells. Blood92,362–367 (1998).
  Medline CASGoogle Scholar
• 39  Murohara T, Ikeda H, Duan J et al.: Transplanted cord blood-derived endothelial precursor cells augment postnatal neovascularization. J. Clin. Invest.105,1527–1536 (2000).
  Medline CASGoogle Scholar
• 40  Yeh ETH, Zhang S, Wu HD, Körbling M, Willerson JT, Estrov Z: Transdifferentiation of human peripheral blood CD34⁺-enriched cell population into cardiomyocytes, endothelial cells, and smooth muscle cells in vivo. Circulation108,2070–2073 (2003).
  MedlineGoogle Scholar
• 41  Kawamoto A, Gwon HC, Iwaguro H et al.: Therapeutic potential of ex vivo expanded endothelial progenitor cells for myocardial ischemia. Circulation103,634–637 (2001).
  Medline CASGoogle Scholar
• 42  Kawamoto A, Tkebuchava T, Nishimura H et al.: Intramyocardial transplantation of autologous endothelial progenitor cells for therapeutic neovascularization of myocardial ischemia. Circulation107,461–468 (2003).
  MedlineGoogle Scholar
• 43  Fuchs S, Baffour R, Zhou YF et al.: Transendocardial delivery of autologous bone marrow enhances collateral perfusion and regional function in pigs with chronic experimental myocardial ischemia. J. Am. Coll. Cardiol.37,1726–1732 (2001).
  Medline CASGoogle Scholar
• 44  Kalka C, Masuda H, Takahashi T et al.: Transplantation of ex vivo expanded endothelial progenitor cells for therapeutic neovascularization. Proc. Natl Acad. Sci. USA97,3422–3427 (2000).
  Medline CASGoogle Scholar
• 45  Schuh A, Liehen EA, Sasse A et al.: Transplantation of endothelial progenitor cells improves neovascularization and left ventricular function after myocardial infarction in a rat model. Basic Res. Cardiol.103,69–77 (2008).
  MedlineGoogle Scholar
• 46  Ziebart T, Yoon CH, Trepels T et al.: Sustained persistence of transplanted proangiogenic cells contributes to neovascularization and cardiac function after ischemia. Circ. Res.103,1327–1334 (2008).
  Medline CASGoogle Scholar
• 47  Pittenger MF, Mackay AM, Beck SC et al.: Multilineage potential of adult human mesenchymal stem cells. Science284,143–147 (1999).▪▪ Landmark study showing the potential of mesenchymal stem cells.
  Medline CASGoogle Scholar
• 48  Pittenger MF, Martin BJ: Mesenchymal stem cells and their potential as cardiac therapeutics. Circ. Res.95,9–20 (2004).
  Medline CASGoogle Scholar
• 49  Dai W, Hale SL, Martin B et al.: Allogeneic mesenchymal stem cell transplantation in postinfarcted rat myocardium. Short- and long-term effects. Circulation112,214–223 (2005).
  MedlineGoogle Scholar
• 50  Schuleri KH, Amado LC, Boyle AJ et al.: Early improvement in cardiac tissue perfusion due to mesenchymal stem cells. Am. J. Physiol. Heart Circ. Physiol.294(5),H2002–H2011 (2008).
  Medline CASGoogle Scholar
• 51  Tang J, Wang J, Yang J et al.: Mesenchymal stem cells over-expressing SDF-1 promote angiogenesis and improve heart function in experimental myocardial infarction in rats. Eur. J. Cardiothorac. Surg.36,644–650 (2009).
  MedlineGoogle Scholar
• 52  Kinnaird T, Stabile E, Burnett MS et al.: Marrow-derived stromal cells express genes encoding a broad spectrum of arteriogenic cytokines and promote in vitro and in vivo arteriogenesis through paracrine mechanisms. Circ. Res.94,678–685 (2004).
  Medline CASGoogle Scholar
• 53  Wang JS, Shum-Tim D, Chedrawy E, Chiu R: The coronary delivery of marrow stromal cells for myocardial regeneration: pathophysiological and therapeutic implications. J. Thorac. Cardiovasc. Surg.122,699–705 (2001).
  Medline CASGoogle Scholar
• 54  Kinnaird TD, Stabile E, Burnett MS et al.: Local delivery of marrow-derived stromal cells augments collateral perfusion through paracrine mechanisms. Circulation109,1543–1549 (2004).
  Medline CASGoogle Scholar
• 55  Losordo DW, Dimmeler S: Therapeutic angiogenesis and vasculaogenesis for ischemic disease. Part I: angiogenic cytokines. Circulation109,2487–2491 (2004).▪ Good review on angiogenic cytokines.
  MedlineGoogle Scholar
• 56  Renault MA, Roncalli J, Togers J et al.: The Hedgehog transcription factor Gli3 modulates angiogenesis. Circ. Res.105,818–826 (2009).
  Medline CASGoogle Scholar
• 57  Renault MA, Losordo DW: Therapeutic myocardial angiogenesis. Microvasc. Res.74,159–171 (2007).▪ Good review on therapeutic angiogenesis.
  Medline CASGoogle Scholar
• 58  Suzuki K, Murtuza B, Smolenski RT et al.: Cell transplantation for the treatment of acute myocardial infarction using vascular endothelial growth factor-expressing skeletal myoblasts. Circulation104,I207–I212 (2001).
  Medline CASGoogle Scholar
• 59  Yang J, Zhou W, Zheng W et al.: Effects of myocardial transplantation of marrow mesenchymal stem cells transfected with vascular endothelial growth factor for the improvement of heart function and angiogenesis after myocardial infarction. Cardiology107,17–29 (2007).
  MedlineGoogle Scholar
• 60  Payne TR, Oshima H, Okada M et al.: A relationship between vascular endothelial growth factor, angiogenesis, and cardiac repair after muscle stem cell transplantation into ischemic hearts. J. Am. Coll. Cardiol.50,1677–1684 (2007).
  Medline CASGoogle Scholar
• 61  Rong SL, Lu YX, Liao YH et al.: Effects of transplanted myoblasts transfected with human growth hormone gene on improvement of ventricular function of rats. Chin. Med. J.121,347–354 (2008).
  Medline CASGoogle Scholar
• 62  Urbich C, Aicher A, Heeschen E et al.: Soluble factors released by endothelial progenitor cells promote migration of endothelial cells and cardiac resident progenitor cells. J. Mol. Cell. Cardiol.39,733–742 (2005).
  Medline CASGoogle Scholar
• 63  Christman KL, Vardanian AJ, Fang Q et al.: Injectable fibrin scaffold improves cell transplant survival, reduces infarct expansion, and induces neovasculature formation in ischemic myocardium. J. Am. Coll. Cardiol.44,654–660 (2004).
  Medline CASGoogle Scholar
• 64  Christman KL, Fang Q, Yee MS et al.: Enhanced neovasculature formation in ischemic myocardium following delivery of pleiotrophin plasmid in a biopolymer. Biomaterials26,1139–1144 (2005).
  Medline CASGoogle Scholar
• 65  Hsieh PC, Davis ME, Gannon C et al.: Controlled delivery of PDGF-BB for myocardial protection using injectable self-assembling peptide nanofibers. J. Clin. Invest.116,237–248 (2006).
  Medline CASGoogle Scholar
• 66  Fujimoto KL, Ma Z, Nelson DM et al.: Synthesis, characterization and therapeutic efficacy of biodegradable, thermo-responsive hydrogel designed for application in chronic infracted myocardium. Biomaterials30,4357–4368 (2006).
  Google Scholar
• 67  Ott HC, Matthiesen TS, Goh SK et al.: Perfusion-decellularized matrix: using nature’s platform to engineer a bioartificial heart. Nat. Med.14,213–221 (2008).
  Medline CASGoogle Scholar
• 68  Inamori M, Mizumoto H, Kajiwara T: An approach for formation of vascularized liver tissue by endothelial cell-covered hepatocyte spheroid integration. Tissue Eng. Part A15,2029–2037 (2009).
  Medline CASGoogle Scholar
• 69  Tse HF, Kwong YL, Chan JK, Lo G, Ho CL, Lau CP: Angiogenesis in ischaemic myocardium by intramyocardial autologous bone marrow mononuclear cell implantation. Lancet361,47–49 (2003).
  MedlineGoogle Scholar
• 70  Perin EC, Dohmann HF, Borojevic R et al.: Transendocardial, autologous bone marrow cell transplantation for severe, chronic ischemic heart failure. Circulation107,2294–2302 (2003).
  MedlineGoogle Scholar
• 71  Erbs S, Linke A, Schächinger V et al.: Restoration of microvascular function in the infarct-related artery by intracoronary transplantation of bone marrow progenitor cells in patients with acute myocardial infarction: the Doppler Substudy of the Reinfusion of Enriched Progenitor Cells and Infarct Remodeling in Acute Myocardial Infarction (REPAIR-AMI) trial. Circulation116,366–374 (2007).
  MedlineGoogle Scholar
• 72  Losordo DW, Schatz RA, White CJ et al.: Intramyocardial transplantation of autologous CD34⁺ stem cells for intractable angina: a Phase I/IIa double-blind, randomized controlled trial. Circulation115,3165–3172 (2007).
  MedlineGoogle Scholar
• 73  Hendrikx M, Hensen K, Clijsters C et al.: Recovery of regional but not global contractile function by the direct intramyocardial autologous bone marrow transplantation: results from a randomized controlled clinical trial. Circulation114(Suppl. 1),I101–I107 (2006).
  MedlineGoogle Scholar
• 74  Fuchs S, Dib N, Cohen BM et al.: A randomized, double-blind, placebo-controlled, multicenter, pilot study on the safety and feasibility of catheter-based intramyocardial injection of AdVEGF121 in patients with refractory advanced coronary artery disease. Catheter Cardiovasc. Interv.68,372–378 (2006).
  MedlineGoogle Scholar
• 75  Dohman HF, Perin EC, Takiya CM et al.: Transendocardial autologous bone marrow mononuclear cell injection in ischemic heart failure: postmortem anatomicopathologic and immunohistochemical findings. Circulation112,521–526 (2005).
  MedlineGoogle Scholar