Crowdsourced science and genetic insights for personalizing medicine: beginning to deliver the goods
References
- 1 Shirky C. Collective action and institutional challenges. In: Here Comes Everybody: The Power of Organizing Without Organizations (1st Edition). Penguin Press, NY, USA, 143–160 (2008).
- 2 Eiben CB, Siegel JB, Bale JB et al. Increased Diels-Alderase activity through backbone remodeling guided by FoldIt players. Nat. Biotechnol.30,190–192 (2012).
- 3 Khatib F, DiMaio F, Foldit Contenders Group, Foldit Void Crushers Group et al. Crystal structure of a monomeric retroviral protease solved by protein folding game players. Nat. Struct. Mol. Biol.18(10),1175–1177 (2011).
- 4 What happened to personalized medicine? Nat. Biotechnol.30(1),1 (2012).
- 5 Swan M. Crowdsourced health research studies: an important emerging complement to clinical trials in the public health research ecosystem. J. Med. Internet Res.14(2),e46 (2012).
- 6 Do CB, Tun JY, Dorfman E et al. Web-based genome-wide association study identified two novel loci and a substantial genetic component for Parkinson’s Disease. PLoS Genet.7(6),e1002141 (2011).
- 7 Callaway E. Gene hunt is on for mental disability. Nature484,302–303 (2012).
- 8 West L, Vidwans SJ, Campbell NP et al. A novel classification of lung cancer into molecular subtypes. PLoS ONE7(2),e31906 (2012).
- 101 SETI@home. http://setiathome.berkeley.edu (Accessed 18 May 2012)
- 102 McGonigal J. We spend 3 billion hours a week as a planet playing videogames. Is it worth it? How could it be MORE worth it? www.ted.com/conversations/44/we_spend_3_billion_hours_a_wee.html (Accessed 10 May 2012)
- 103 The Great Sunflower Project. www.greatsunflower.org (Accessed 20 May 2012)
- 104 FoldIt. http://fold.it/portal/info/science (Accessed 20 May 2012)
- 105 Emerging Health Innovator SEED award winners selected. Healthymagination challenge. http://challenge.healthymagination.com/health (Accessed 24 May 2012)
- 106 National Human Genome Research Institute. DNA sequencing costs. www.genome.gov/sequencingcosts. (Accessed 24 May 2012)
- 107 23andMe. www.23andme.com/research (Accessed 20 May 2012)
- 108 ClinVar. www.ncbi.nlm.nih.gov/clinvar (Accessed 26 May 2012)
- 109 DECIPHER. http://decipher.sanger.ac.uk (Accessed 26 May 2012)
- 110 Cancer Commons. www.cancercommons.org (Accessed 23 May 2012)
- 111 A lung cancer disease model: live version. http://lcdm.cancercommons.org/lc/index.php/A_Lung_Cancer_Molecular_Disease_Model (Accessed 24 May 2012)
- 112 Swan M. DIYgenomics crowdsourced health research studies: personal wellness and preventative medicine through collective intelligence. Association for the Advancement of Artificial Intelligence Technical Report SS-12-05. Self-tracking and collective intelligence for personal wellness (2011). www.aaai.org/ocs/index.php/SSS/SSS12/paper/download/4293/4681
- 113 Shapiro AD. Gamers and genomics: crowdsourcing DNA research. www.theworld.org/2012/04/gamers-genomics-crowdsourcing-dna-research-using-phylo (Accessed 13 May 2012)
- 114 Phylo. http://phylo.cs.mcgill.ca (Accessed 20 May 2012)
- 115 American College of Medical Genetics and Genomics. www.acmg.net//AM/Template.cfm?Section=Home3 (Accessed 20 May 2012)
- 116 Corbin Z. Whitehouse petitioned to make research free to access. www.nature.com/news/white-house-petitioned-to-make-research-free-to-access-1.10723 (Accessed 25 May 2012)
- 117 Crowdsourcing for personalized medicine. www.crowdsourcing.org/navigate-search?q=personalized%20medicine (Accessed 25 May 2012)